37909-88-9

Basic information

• Product Name: Thiophene, 2-[1,1'-biphenyl]-4-yl-
• CAS NO: 37909-88-9
• Molecular Formula: C16H12S
• Molecular Weight: 236.337
• Mol File: 37909-88-9.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Thiophene, 2-[1,1'-biphenyl]-4-yl-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiophene, 2-[1,1'-biphenyl]-4-yl-(37909-88-9)
• EPA Substance Registry System: Thiophene, 2-[1,1'-biphenyl]-4-yl-(37909-88-9)

Safety Data

• Hazardous Substances Data: 37909-88-9(Hazardous Substances Data)

Upstream product

• 92-52-4 biphenyl 
• 188290-36-0 thiophene 
• 6165-68-0 thiophene boronic acid 
• 133042-63-4 4-bromophenyl sulfurofluoridate 
• 98-80-6 phenylboronic acid 
• 92-66-0 4-bromo-1,1'-biphenyl 
• 72133-72-3 2-iodothiophene 
• 71-43-2 benzene 
• 3185-76-0 2,4,6-tris-biphenyl-4-yloxy-[1,3,5]triazine 
• 1003-09-4 2-bromothiophene 
• 5122-94-1 4-biphenylboronic acid 
• 29079-00-3 4-ethynyl-1,1'-biphenyl 
• 1449482-59-0 2-[3-(toluene-4-sulfonyl)biphenyl-4-yl]furan 
• 40133-22-0 2-(4-bromophenyl)thiophene 

Downstream Products

• 37910-11-5 5-((1,1'-biphenyl)-4-yl)thiophene-2-carboxylic acid 

Relevant articles and documents

Immobilization of palladium nanoparticles on Metformin-functionalized graphene oxide as a heterogeneous and recyclable nanocatalyst for Suzuki coupling reactions and reduction of 4-nitrophenol

In this study, Pd nanoparticles supported on Metformin modified graphene oxide (GO-Met-Pd) is proposed as a green heterogeneous catalyst. The structural properties of the as-synthesized nanocatalyst were determined by X-ray diffraction (XRD), Fourier transformed infrared (FT-IR) spectroscopy, transmission electron microscopy (TEM), field emission scanning electron microscopy (FESEM), energy dispersive X-ray spectroscopy (EDS), wavelength-dispersive X-ray spectroscopy (WDX) and inductively coupled plasma (ICP). Activity of the catalyst was investigated by focusing on the Suzuki-Miyaura coupling reaction and room-temperature reduction of 4-nitrophenol (4-NP), as model reactions. The catalyzed reactions provided high yields of biphenyl compounds through the Suzuki-Miyaura reaction and outlined highly efficient conversion of 4-NP to its reduced form. Moreover, no significant Pd leaching was detected in the reaction solutions and the catalyst could be recovered, at least, 6 times without any considerable loss of its catalytic activity.

Photochemical (Hetero-)Arylation of Aryl Sulfonium Salts

The construction of (hetero)biaryls, which are ubiquitous scaffolds among medical substances, functional materials, and agrochemicals, constitutes a key application of cross-coupling methods. However, these usually require multiple synthetic steps. Herein, we report a simple photoinduced and catalyst-free C-H/C-H (hetero)arylation cross-coupling through aryl thianthrenium salts, which are formed site-selectively by direct C-H functionalization. The key to this approach is the UV-light, which can disrupt the C-S bond to form thianthrene radical cations and aryl radicals.

Furan- and thiophene-2-carbonyl amino acid derivatives activate hypoxia-inducible factor via inhibition of factor inhibiting hypoxia-inducible factor-1

Induction of a series of anti-hypoxic proteins protects cells during exposure to hypoxic conditions. Hypoxia-inducible factor-α (HIF-α) is a major transcription factor that orchestrates this protective effect. To activate HIF exogenously, without exposing