381226-84-2

Basic information

• Product Name: 6-METHYL-2,3-DIHYDRO-PYRIDO[3,2-B][1,4]OXAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: 6-METHYL-2,3-DIHYDRO-PYRIDO[3,2-B][1,4]OXAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER;tert-Butyl 6-methyl-2H-pyrido[3,2-b][1,4]oxazine-4(3H)-carboxylate
• CAS NO: 381226-84-2
• Molecular Formula: C₁₃H₁₈N₂O₃
• Molecular Weight: 250.296
• Mol File: 381226-84-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-METHYL-2,3-DIHYDRO-PYRIDO[3,2-B][1,4]OXAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 6-METHYL-2,3-DIHYDRO-PYRIDO[3,2-B][1,4]OXAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER(381226-84-2)
• EPA Substance Registry System: 6-METHYL-2,3-DIHYDRO-PYRIDO[3,2-B][1,4]OXAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER(381226-84-2)

Safety Data

• Hazardous Substances Data: 381226-84-2(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 20567-67-3 6-methyl-3,4-dihydro-2h-pyrido[3,2-b][1,4]oxazine 
• 20348-16-7 2-amino-3-hydroxy-6-methylpyridine 
• 15128-90-2 6-methyl-2-nitropyridin-3-ol 
• 20348-10-1 6-methyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4h)-one 

Downstream Products

• 855313-34-7 6-[2-(3-methyl-4-nitro-phenoxy)-ethyl]-2,3-dihydro-pyrido[3,2-b][1,4]oxazine-4-carboxylic acid tert-butyl ester 

Relevant articles and documents

Non-peptidic αvβ3 antagonists containing indol-1-yl propionic acids

We describe the synthesis and structure/activity relationship of RGD mimetics that are potent inhibitors of the integrin αvβ 3. Indol-1-yl propionic acids containing a variety of basic moieties at the 5-position, as well as substitutions alpha and beta to the carboxy terminus were synthesized and evaluated. Novel compounds with improved potency have been identified.

Cycloalkyl alkanoic acids as integrin receptor antagonists derivatives

The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the αvβ3 and/or αvβ5 integrin.