382-45-6 Usage
Description
Adrenosterone, also known as androgenic steroid, is a steroid hormone with weak androgenic effects. It is an off-white to pale yellow solid and is known for its androgenic activity.
Uses
Used in Pharmaceutical Industry:
Adrenosterone is used as a pharmaceutical agent for its androgenic activity. It is utilized in the development and production of medications that target hormonal imbalances and conditions related to androgen levels.
Used in Sports and Fitness Industry:
Adrenosterone is used as a performance-enhancing substance for its androgenic effects. It is taken by athletes and bodybuilders to improve muscle mass, strength, and overall performance, although its use may be controversial and subject to regulations.
Used in Research and Development:
Adrenosterone is used as a research compound for studying the effects of androgens on the human body. It aids scientists in understanding the role of androgens in various physiological processes and the development of new drugs and therapies targeting androgen-related conditions.
Used in Veterinary Medicine:
Adrenosterone is used as a veterinary drug for treating hormonal imbalances and related conditions in animals. It helps in maintaining proper hormonal levels and ensuring the overall health and well-being of animals.
Purification Methods
Dissolve adrenosterone i n Me2CO, decolorise it with charcoal, filter, add H2O, Me2CO evaporate and the solid is recrystallised from aqueous EtOH. Also recrystallise it from Et2O or Et2O/pentane and dry it at 110o/0.1mm for 2hours. It can be sublimed under high vacuum. [Reichstein Helv Chim Acta 20 953, 979 1937, Mason et al. J Biol Chem 116 267 1936, Beilstein 7 III 4601.]
Check Digit Verification of cas no
The CAS Registry Mumber 382-45-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,8 and 2 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 382-45:
(5*3)+(4*8)+(3*2)+(2*4)+(1*5)=66
66 % 10 = 6
So 382-45-6 is a valid CAS Registry Number.
InChI:InChI=1/C19H24O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-14,17H,3-8,10H2,1-2H3/t13-,14-,17+,18-,19-/m0/s1
382-45-6Relevant articles and documents
Reductive Alkylation of Enediones. 2. Synthesis of Corticosteroids
Stork, Gilbert,Logusch, E. W.
, p. 1219 - 1220 (1980)
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A straightforward chemical synthesis of 17-ketosteroids by cleavage of the C-17-dihydroxy acetone side chain in corticosteroids
Le Pera, Adolfo,Leggio, Antonella,Siciliano, Carlo,Di Gioia, Maria L.,Napoli, Anna,Sindona, Giovanni,Liguori, Angelo
, p. 139 - 142 (2003)
A facile and convenient approach to 17-ketosteroids is described. Treatment of steroids containing the C-17-dihydroxy acetone side chain with an excess of sodium methoxide in dry 1,4-dioxane under reflux, affords high yields of the corresponding 17-ketosteroids that are recovered as pure products, without the need of further purification.
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Reichstein
, p. 978,987 (1937)
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Iodine-promoted cleavage of the C-17-dihydroxyacetone side chain of corticosteroids in aqueous ammonia water
Sun, Liang,Geng, Xin,Liu, Lanhai,Jiang, Chenggang,Wang, Cunde
, p. 22 - 23 (2009)
A convenient approach to 17-ketosteroids by the iodine-promoted cleavage of the C-17-dihydroxy acetone side chain of corticosteroids is described. Treatment of steroids containing the C-17-dihydroxyacetone side chain with iodine and an excess of aqueous ammonia in acetonitrile at 50°ffords high yields of the corresponding 17-ketosteroids.
HYDROXYSTEROID COMPOUNDS, THEIR INTERMEDIATES, PROCESS OF PREPARATION, COMPOSITION AND USES THEREOF
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, (2016/02/09)
The present invention relates to novel steroidal compounds of formula (I), process for preparation of the same and composition comprising these compounds.
