38201-61-5

Basic information

• Product Name: (1)benzothieno(2,3-d)pyrimidin-4(1h)-one,2,3,5,6,7,8-hexahydro-3-methyl-2-thio
• Synonyms: (1)benzothieno(2,3-d)pyrimidin-4(1h)-one,2,3,5,6,7,8-hexahydro-3-methyl-2-thio;3-methyl-2,3,5,6,7,8-hexahydro-2-thioxo-(1)benzothieno(2,3-d)pyrimidin-4(1h)
• CAS NO: 38201-61-5
• Molecular Formula: C₁₁H₁₂N₂OS₂
• Molecular Weight: 252.35578
• Mol File: 38201-61-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 448.3°Cat760mmHg
• Flash Point: 224.9°C
• Appearance: /
• Density: 1.46g/cm³
• Vapor Pressure: 3.13E-08mmHg at 25°C
• Refractive Index: 1.716
• CAS DataBase Reference: (1)benzothieno(2,3-d)pyrimidin-4(1h)-one,2,3,5,6,7,8-hexahydro-3-methyl-2-thio(CAS DataBase Reference)
• NIST Chemistry Reference: (1)benzothieno(2,3-d)pyrimidin-4(1h)-one,2,3,5,6,7,8-hexahydro-3-methyl-2-thio(38201-61-5)
• EPA Substance Registry System: (1)benzothieno(2,3-d)pyrimidin-4(1h)-one,2,3,5,6,7,8-hexahydro-3-methyl-2-thio(38201-61-5)

Safety Data

• Hazardous Substances Data: 38201-61-5(Hazardous Substances Data)

Usage

Description

(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 2,3,5,6,7,8-hexahydro-3-methyl-2-thio is a complex chemical compound characterized by a benzothieno ring fused to a pyrimidinone ring. It features a six-membered hexahydro ring with a methyl and thio group attached, which may contribute to its unique chemical properties and potential interactions with biological systems. Its heterocyclic nature suggests that it could have pharmaceutical or biological applications, although further research and testing are required to determine its specific uses and properties.

Uses

Used in Pharmaceutical Industry:
(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 2,3,5,6,7,8-hexahydro-3-methyl-2-thio is used as a potential pharmaceutical candidate for [specific application reason, if available] due to its heterocyclic nature and the presence of a thio group, which may allow it to interact with biological systems in unique ways. The sulfur content could also provide distinct chemical properties that are beneficial for drug development.
Used in Biological Research:
In the field of biological research, (1)benzothieno(2,3-d)pyrimidin-4(1H)-one, 2,3,5,6,7,8-hexahydro-3-methyl-2-thio may be utilized as a compound of interest for studying its interactions with biological systems, potentially leading to the discovery of new mechanisms of action or therapeutic targets. Its complex molecular structure and heterocyclic nature make it a promising subject for investigation.

InChI:InChI=1/C11H12N2OS2/c1-13-10(14)8-6-4-2-3-5-7(6)16-9(8)12-11(13)15/h2-5H2,1H3,(H,12,15)

Upstream product

• 51486-13-6 2-(3-Methyl-thioureido)-4,5,6,7-tetrahydrobenzothiophen-3-carbonsaeureethylester 
• 38201-62-6 2-amino-3-(N-methylcarboxamido)-4,5,6,7-tetrahydrobenzothiophene 
• 17356-08-0 thiourea 
• 126105-75-7 4-Imino-3-methyl-3,4,5,6,7,8-hexahydro-1H-benzo[4,5]thieno[2,3-d]pyrimidine-2-thione 
• 4506-71-2 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 556-61-6 methyl thioisocyanate 
• 85716-87-6 ethyl 2-isothiocyanato-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 74-89-5 methylamine 
• 4651-91-6 3-cyano-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene 

Downstream Products

• 59898-79-2 (3-methyl-4-oxo-3,4,5,6,7,8-hexahydro-benzo[4,5]thieno[2,3-d]pyrimidin-2-ylsulfanyl)-acetic acid ethyl ester 
• 59898-74-7 (3-methyl-4-oxo-3,4,5,6,7,8-hexahydro-benzo[4,5]thieno[2,3-d]pyrimidin-2-ylsulfanyl)-acetic acid 
• 79598-26-8 3a-Ethoxy-4-methyl-2-phenyl-3a,4,6,7,8,9-hexahydro-3,10-dithia-4,10b-diaza-cyclopenta[a]fluorene-1,5-dione 
• 79587-91-0 (3-Methyl-4-oxo-3,4,5,6,7,8-hexahydro-benzo[4,5]thieno[2,3-d]pyrimidin-2-ylsulfanyl)-phenyl-acetic acid 
• 337349-66-3 3-methyl-2-(prop-2-yn-1-ylthio)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one 

Relevant articles and documents

REACTIONS WITH ETHYL-4,5,6,7-TETRAHYDRO-2-ISOTHIOCYANATO-1-BENZOTHIOPHENE-3-CARBOXYLATE. SYNTHESIS OF SOME NOVEL HETEROCYCLIC COMPOUNDS WITH POTENTIAL HYPNOTIC ACTIVITY

Ethyl-4,5,6,7-tetrahydro-2-isothiocyanato-1-benzothiophene-3-carboxylate (2), prepared from ethyl-4,5,6,7-tetrahydro-2-amino-1-benzothiophene-3-carboxylate (1) by the thiophosgene method, was converted with nucleophiles into benzothienopyrimidine derivatives (3-5) and (7) either directly or through thiourethane (6a).The tricyclic, benzothienopyrimidine system (8) and (9) were obtained either from the isothiocyanate (2) or the thiourethane (6a), while the tetracyclic systems, triazolothienopyrimidines (10,11); tetrazolothienopyrimidines (12,13) and tetrazepino derivative (14), were obtained from 2,3,5,6,7,8-hexahydro-3-amino-2-hydrazino-1-benzothienopyrimidine-4(3H)-one (9).Preliminary pharmacological screening revealed that some of the new compounds exhibited hypnotic activity. - Key words: Thienopyrimidines; hypnotic activity

Interaction of heterothiocumulenes with 2-amino-3-cyanothiophenes: Formation of thienopyrimidines

Thieno-fused(1,3)-thiazine, 4-imino-2-thioxo-2,4-dihydro-1H-thieno(1,3)-thiazine (2) has been directly synthesised by the reaction of o-aminonitrile (1a) with carbon disulphide.Thiazine (2) on reaction with primary aromatic amines leads to thieno2

Synthesis of 3 substituted thieno[2,3 d]pyrimidin 4(3H) one 2 mercaptoacetic acids and their ethyl esters for pharmacological screening

3 Substituted thieno[2,3 d]pyrimidin 4(3H) one 2 mercaptoacetic acids and their ethyl esters were synthesized from 2 mercaptothieno[2,3 d]pyrimidin 4 (3H) ones, which were obtained by cyclization of thienylthioureas in acidic medium. Analgesic, anti inflammatory, and anticonvulsant activities were found in some of these compounds. Significant antimicrobial activity was exhibited by thienylthioureas.