38237-76-2

Basic information

• Product Name: 4-aminohexanoylphenone
• Synonyms: 4-aminohexanoylphenone;4''-AMINOHEXANOPHENONE,98.0+%(GC)(T);4'-Aminohexanophenone;4-Hexanoylaniline
• CAS NO: 38237-76-2
• Molecular Formula: C₁₂H₁₇NO
• Molecular Weight: 191.30
• Mol File: 38237-76-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 85 °C
• Boiling Point: 327.03°C (rough estimate)
• Flash Point: 162°C
• Appearance: /
• Density: 1.0096 (rough estimate)
• Vapor Pressure: 6.65E-05mmHg at 25°C
• Refractive Index: 1.5220 (estimate)
• Solubility: soluble in Methanol
• CAS DataBase Reference: 4-aminohexanoylphenone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-aminohexanoylphenone(38237-76-2)
• EPA Substance Registry System: 4-aminohexanoylphenone(38237-76-2)

Safety Data

• RIDADR: 2811
• RTECS: MP4450000
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 38237-76-2(Hazardous Substances Data)

Usage

General Description

4-aminohexanoylphenone, also known as 4-AHPK, is a chemical compound commonly used in the manufacturing of pharmaceuticals and organic synthesis. It is a ketone derivative with a six-carbon chain containing an amino group and a phenyl group. 4-AHPK is often utilized as a starting material for the production of various heterocyclic compounds and as a building block for the synthesis of new drugs. It has been studied for its potential in anti-tumor and anti-inflammatory activities, as well as its ability to inhibit enzymes involved in pathological processes. Additionally, 4-aminohexanoylphenone has shown promise in the development of new chemical entities and drug candidates. Despite its potential therapeutic uses, further research is needed to fully understand the biological and pharmacological properties of this chemical.

InChI:InChI=1/C12H17NO/c1-2-3-4-5-12(14)10-6-8-11(13)9-7-10/h6-9H,2-5,13H2,1H3

Upstream product

• 7295-50-3 1-(4-chlorophenyl)hexan-1-one 
• 33228-41-0 acetic acid-(4-hexanoyl-anilide) 
• 142-61-0 Hexanoyl chloride 
• 103-84-4 Acetanilid 
• 100-19-6 (4-nitrophenyl)ethanone 
• 71-36-3 butan-1-ol 
• 108-86-1 bromobenzene 
• 7295-46-7 1-(4-bromophenyl)-1-hexanone 

Downstream Products

• 100875-55-6 N-(4-hexanoyl-phenyl)-N'-methyl-thiourea 

Relevant articles and documents

Preparation method of aryl ketone compound

The invention provides a preparation method of an aryl ketone compound, and belongs to the technical field of compound synthesis. The method comprises the following steps: under the action of a silver catalyst and water, carrying out reaction on aryl alkyne with a structure as shown in a formula 1 in a solvent at 60-120 DEG C for 12-48 hours, and separating and purifying a product after the reaction is finished, so as to obtain the single aryl ketone compound with a structure as shown in a formula I, the raw materials are easy to obtain, the experimental operation is simple, the yield of the prepared single aryl ketone compound is good, and gram-scale experiments can be carried out.

Palladium-catalysed transfer hydrogenation of aromatic nitro compounds - An unusual chain elongation

Aromatic nitro compounds are reduced via transfer hydrogenation in the presence of palladium on magnesium-lanthanum mixed oxide support in ethanol yielding the corresponding amines. With several acetophenone derivatives, the reduction was accompanied by c

Rapid microwave assisted hydration of internal arylalkynes in the presence of PTSA: an efficient regioselective access to carbonyl compounds

A metal-free procedure for the regioselective hydration of internal arylalkynes under microwave irradiation is described. The reaction promoted by PTSA takes place rapidly in EtOH and regioselectively afforded in good yields various carbonyl compounds 2.