383127-24-0 Usage
Structure
Pyrrolidine derivative with a methylpropyl group attached to the nitrogen atom of the pyrrolidine ring
Usage
Organic synthesis as a building block for the preparation of various pharmaceuticals and agrochemicals, chiral auxiliary in asymmetric synthesis, potential applications in the field of materials science and as a ligand in coordination chemistry
Safety
Handle with caution, may have hazardous properties, should be used in a controlled manner in a laboratory setting.
Check Digit Verification of cas no
The CAS Registry Mumber 383127-24-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,8,3,1,2 and 7 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 383127-24:
(8*3)+(7*8)+(6*3)+(5*1)+(4*2)+(3*7)+(2*2)+(1*4)=140
140 % 10 = 0
So 383127-24-0 is a valid CAS Registry Number.
383127-24-0Relevant articles and documents
One-Pot Biocatalytic Cascade Reduction of Cyclic Enimines for the Preparation of Diastereomerically Enriched N-Heterocycles
Thorpe, Thomas W.,France, Scott P.,Hussain, Shahed,Marshall, James R.,Zawodny, Wojciech,Mangas-Sanchez, Juan,Montgomery, Sarah L.,Howard, Roger M.,Daniels, David S. B.,Kumar, Rajesh,Parmeggiani, Fabio,Turner, Nicholas J.
, p. 19208 - 19213 (2019/12/24)
Ene-reductases (EREDs) catalyze the reduction of electron-deficient C=C bonds. Herein, we report the first example of ERED-catalyzed net reduction of C=C bonds of enimines (α,β-unsaturated imines). Preliminary studies suggest their hydrolyzed ring-open ω-amino enones are the likely substrates for this step. When combined with imine reductase (IRED)-mediated C=N reduction, the result is an efficient telescoped sequence for the preparation of diastereomerically enriched 2-substituted saturated amine heterocycles.
