383130-99-2 Usage
Description
5-(3-Bromophenyl)-4H-1,2,4-triazol-3-amine is a chemical compound that belongs to the class of triazoles. It features a triazole ring fused with an amine group and a bromophenyl substituent, which may contribute to its potential biological activities and applications in medicinal chemistry.
Uses
Used in Pharmaceutical Industry:
5-(3-Bromophenyl)-4H-1,2,4-triazol-3-amine is used as a potential active pharmaceutical ingredient for its possible antifungal, antibacterial, and anticancer properties. Its unique structure may allow for the development of new drugs targeting a variety of diseases and conditions.
Used in Drug Development:
In the field of drug development, 5-(3-Bromophenyl)-4H-1,2,4-triazol-3-amine is utilized as a compound of interest for further research and testing. Its exploration may lead to the discovery of new therapeutic agents with improved efficacy and safety profiles.
Further research and testing are necessary to fully understand the pharmacological properties and potential uses of 5-(3-Bromophenyl)-4H-1,2,4-triazol-3-amine, ensuring its safe and effective application in various medical fields.
Check Digit Verification of cas no
The CAS Registry Mumber 383130-99-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,8,3,1,3 and 0 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 383130-99:
(8*3)+(7*8)+(6*3)+(5*1)+(4*3)+(3*0)+(2*9)+(1*9)=142
142 % 10 = 2
So 383130-99-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H7BrN4/c9-6-3-1-2-5(4-6)7-11-8(10)13-12-7/h1-4H,(H3,10,11,12,13)
383130-99-2Relevant articles and documents
A green one-pot synthesis of 3(5)-substituted 1,2,4-triazol-5(3)-amines as potential antimicrobial agents
Beyzaei, Hamid,Khosravi, Zahra,Aryan, Reza,Ghasemi, Behzad
, p. 2565 - 2573 (2019/07/04)
Abstract: An efficient procedure was proposed for the synthesis of 3(5)-substituted 1,2,4-triazol-5(3)-amines via a one-pot reaction of thiourea, dimethyl sulfate and various hydrazides. 1,2,4-Triazole derivatives were prepared in aqueous media under mild conditions while adhering to some principles of green chemistry. The products were easily isolated in 83–95% yields without any need for further purification. Inhibitory activities of all synthetic compounds were assessed against a variety of Gram-positive and Gram-negative pathogenic bacteria as well as some fungal pathogens. The best antibacterial effects were observed with 3(5)-phenyl-1H-1,2,4-triazol-5(3)-amine according to its MIC values (4–8?μg?mL?1). All compounds were successful in blocking the growth of fungi. Acceptable antioxidant properties were observed only with 3(5)-(4-nitrophenyl)-1H-1,2,4-triazol-5(3)-amine. Graphic abstract: 3(5)-Substituted 1,2,4-triazol-5(3)-amines were efficiently prepared via a one-pot reaction of thiourea, dimethyl sulfate and various hydrazides in water as the solvent. Inhibitory activity of all synthesized derivatives was proved according to their MIC, MBC and MFC values. It is found that they are potential antifungal agents.[Figure not available: see fulltext.].