38484-42-3

Basic information

• Product Name: 1-Pentyn-3-ol, 3,4,4-trimethyl-, (R)-
• CAS NO: 38484-42-3
• Molecular Formula: C8H14O
• Molecular Weight: 126.199
• Mol File: 38484-42-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1-Pentyn-3-ol, 3,4,4-trimethyl-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pentyn-3-ol, 3,4,4-trimethyl-, (R)-(38484-42-3)
• EPA Substance Registry System: 1-Pentyn-3-ol, 3,4,4-trimethyl-, (R)-(38484-42-3)

Safety Data

• Hazardous Substances Data: 38484-42-3(Hazardous Substances Data)

Upstream product

• 75-97-8 3,3-dimethyl-butan-2-one 
• 4301-14-8 acetylenemagnesium bromide 
• 74-86-2 acetylene 
• 75-20-7 calcium carbide 
• 1066-26-8 sodium acetylide 
• 97638-22-7 3,4,4-trimethyl-1-pentyn-3-ol hydrogen phthalate 
• 38484-41-2 3,4,4-trimethylpent-1-yn-3-ol 
• 71-43-2 benzene 
• 60-29-7 diethyl ether 
• 10575-72-1 1-bromo-3,4,4-trimethyl-penta-1,2-diene 
• 75-64-9 tert-butylamine 
• 75-04-7 ethylamine 

Downstream Products

• 38484-41-2 (S)-3,4,4-trimethyl-1-pentyn-3-ol 
• 4457-08-3 (+/-)-1-chloro-3,4,4-trimethyl-penta-1,2-diene 
• 2809-84-9 2-(tert-butyl)-but-1-en-3-yne 
• 100052-44-6 (3E,5E)-6,7,7-trimethyl-octa-3,5-dien-2-one 
• 91716-37-9 1-(1-tert-butyl-1-methyl-prop-2-ynyloxy)-2,2,2-trichloro-ethanol 
• 66725-84-6 1,1,1-trichloro-5-hydroxy-5,6,6-trimethyl-hept-3-yn-2-one 
• 30278-64-9 1-(Diethyl-propoxymethyl-silanyl)-3,4,4-trimethyl-pent-1-yn-3-ol 
• 7576-25-2 4,4-dimethyl-3-methyliden-2-pentanon 
• 144562-22-1 3,4,4-trimethyl-pent-2-enal 
• 35476-41-6 2,3,3-trimethyl-pent-4-yn-2-ol 
• 16487-13-1 1-chloro-3,4,4-trimethyl-penta-1,2-diene 
• 16487-11-9 methyl-tert-butylpropargyl chloride 
• 10575-72-1 1-bromo-3,4,4-trimethyl-penta-1,2-diene 
• 50838-79-4 2,2,3,8,9,9-hexamethyl-dec-4t-en-6-yne-3,8-diol 

Relevant articles and documents

Polycyclic bridgehead acetals with enol functionality: one-pot assembly from aliphatic ketones and acetylene in KOH/DMSO suspension

Aliphatic and cycloaliphatic ketones undergo selective multi-site cascade C–H functionalization with acetylene in the KOH/DMSO superbase suspension under mild conditions (70–80?°C, 0.5–1.0?h) to afford in one synthetic operation polycyclic bridgehead acet

Alkynylation of aldehydes and ketones using the Bu4NOH/H 2O/DMSO catalytic composition: A wide-scope methodology

The Favorsky reaction of a wide range of aldehydes and ketones with alkynes has been implemented under mild conditions (5-20 C). Using a Bu 4NOH/H2O/DMSO catalytic system, propargylic alcohols are formed cleanly in 39-93% (mostly 72-93%) yields and with ca. 100% selectivity. The method is suitable for aliphatic, aromatic, and heteroaromatic aldehydes and ketones, and for aliphatic, aromatic, and functionalized acetylenes. Thus, this represents the most general and efficient protocol to achieve the Favorsky reaction. Copyright

REACTIONS OF NITROGEN NUCLEOPHILES WITH 1-BROMOALLENES: REGIOSELECTIVE SYNTHESIS OF PROPARGYLAMINES

The results of a study on the reactivity of 3-alkyl- and 3,3-dialkyl-1-bromo-1,2-dienes 2 towards nitrogen nucleophiles, such as aqueous ammonia, lithium amide, aliphatic and aromatic amines allowed us to propose new methods for the synthesis of propargylamines, 1, with an available acetylenic hydrogen.The regio- and the stereoselectivity of these reactions are examined and possible mechanisms are discussed.