3864-18-4

Basic information

• Product Name: 23DIMETHYLBIPHENYL
• Synonyms: Biphenyl,2,3-dimethyl- (6CI,7CI,8CI); 2,3-Dimethyl-1,1'-biphenyl; 2,3-Dimethylbiphenyl
• CAS NO: 3864-18-4
• Molecular Formula: C₁₄H₁₄
• Molecular Weight: 182.26096
• Mol File: 3864-18-4.mol
• Article Data: 19

Chemical Properties

• Melting Point: 42°C
• Boiling Point: 275.67°C (estimate)
• Flash Point: 117.4°C
• Appearance: /
• Density: 0.9900 (estimate)
• Vapor Pressure: 0.00965mmHg at 25°C
• Refractive Index: 1.5845
• CAS DataBase Reference: 23DIMETHYLBIPHENYL(CAS DataBase Reference)
• NIST Chemistry Reference: 23DIMETHYLBIPHENYL(3864-18-4)
• EPA Substance Registry System: 23DIMETHYLBIPHENYL(3864-18-4)

Safety Data

• Hazardous Substances Data: 3864-18-4(Hazardous Substances Data)

Usage

Description

2,3-Dimethylbiphenyl is an organic compound with a biphenyl core structure, featuring two methyl groups attached at the 2nd and 3rd positions. It is a versatile intermediate in organic synthesis and plays a significant role in the preparation of various chemical compounds.

Uses

Used in Catalyst Preparation:
2,3-Dimethylbiphenyl is used as a reagent in the preparation of carbene complexes, which function as catalysts for Suzuki coupling reactions. These reactions are widely employed in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, due to their ability to form carbon-carbon bonds.
Used in Organic Synthesis:
As an intermediate in organic synthesis, 2,3-Dimethylbiphenyl is utilized in the production of a range of chemical compounds. Its presence in the biphenyl core structure allows for further functionalization and modification, making it a valuable component in the synthesis of various organic molecules.

InChI:InChI=1/C14H14/c1-11-7-6-10-14(12(11)2)13-8-4-3-5-9-13/h3-10H,1-2H3

Upstream product

• 95-47-6 o-xylene 
• 2396-01-2 phenyl radical 
• 13395-76-1 2,3-dimethylcyclohexanone 
• 591-51-5 phenyllithium 
• 63539-35-5 3-Phenyl-octen-⁽³⁾-on-⁽⁷⁾ 
• 87-59-2 2,3-Dimethylaniline 
• 71-43-2 benzene 
• 106-42-3 para-xylene 
• 3893-06-9 5-Methyl-1-phenyl-hepta-trans-1,cis-3,trans-5-trien 
• 108-94-1 cyclohexanone 
• 31599-60-7 1-iodo-2,3-dimethylbenzene 
• 98-80-6 phenylboronic acid 
• 576-23-8 2,3-dimethylbromobenzene 
• 2778-58-7 2,3-Dimethylphenyl-p-toluolsulfonat 

Relevant articles and documents

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A Spiroalkylation Method for the Stereoselective Construction of α-Quaternary Carbons and Its Application to the Total Synthesis of (R)-Puraquinonic Acid

Cyclic α-quaternary carbon stereocenters were prepared from biselectrophillic substrates and an easily prepared chiral bicyclic sulfonyl lactam. This was achieved in two steps by spiroalkylation, employing biphasic reaction conditions with a phase-transfer catalyst, followed by reduction and alkylation with a series of alkyl halide electrophiles. The products of this method were isolated in good yields with with high levels of diastereoselectivity. This methodology was employed in the enantioselective total synthesis of (R)-puraquinonic acid (1) for a late-stage installation of the α-quaternary carbon stereocenter. This enabled the shortest synthesis of 1 to date, an eight-pot sequence providing an overall yield of 14%.

A 2-methyl-3-phenyl-methanol preparation method

The invention relates to a preparation method of 2-methyl-3-phenyl benzyl alcohol. The preparation method comprises the steps of (1) under a lighting condition, enabling 2,3-dimethyl biphenyl to mix and react with chlorine gas at 40-120 DEGC; or, in the presence of an initiator, enabling the 2,3-dimethyl biphenyl to react with sulfuryl chloride or chlorine gas at 40-120 DEG C; (2) implementing an esterification reaction on 2-methyl-3-chloromethyl biphenyl prepared by the step (1) and an esterification reagent in a solvent in the presence of a catalyst; and (3) under an alkaline condition, hydrolyzing an esterification product prepared by the step (2), and controlling pH range within 9-14. The preparation method disclosed by the invention is simple and convenient to operate, relatively low in cost, not high in requirement on equipment and applicable to industrial production. (img file='DDA0000466672690000011. TIF'wi='1528'he='344'/).