38642-49-8

Basic information

• Product Name: benzoylpaeoniflorin
• Synonyms: Benzoylpaeoniflorin
• CAS NO: 38642-49-8
• Molecular Formula: C₃₀H₃₂O₁₂
• Molecular Weight: 584.571
• Product Categories: pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;The group of Paeoniflorin;chemical reagent
• Mol File: 38642-49-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 733.8 °C at 760 mmHg
• Flash Point: 397.6 °C
• Appearance: /
• Density: 1.56 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.682
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 11.52±0.70(Predicted)
• CAS DataBase Reference: benzoylpaeoniflorin(CAS DataBase Reference)
• NIST Chemistry Reference: benzoylpaeoniflorin(38642-49-8)
• EPA Substance Registry System: benzoylpaeoniflorin(38642-49-8)

Safety Data

• Hazardous Substances Data: 38642-49-8(Hazardous Substances Data)

Usage

Description

Benzoylpaeoniflorin is a natural product isolated from Chinese paeony root, known for its ability to inhibit COX-1 and COX-2 in vitro. It exhibits a range of pharmacological properties, including antibacterial, antidiabetic, antitumor, anti-inflammatory, and hepatoprotective effects.

Uses

Used in Pharmaceutical Industry:
Benzoylpaeoniflorin is used as a therapeutic agent for various conditions due to its multifaceted pharmacological properties. Its antibacterial, antidiabetic, antitumor, anti-inflammatory, and hepatoprotective effects make it a promising candidate for the development of new drugs and treatments.
Used in Coronary Heart Disease Treatment:
Benzoylpaeoniflorin is used as a cardioprotective agent for the treatment of coronary heart disease. It functions by increasing the levels of Bcl-2 and decreasing the levels of Bax, which helps in restraining apoptosis in rats with coronary heart disease. This suggests its potential use in reducing apoptosis and improving heart health in patients with coronary conditions.

Clinical claims and research

benzoylpaeoniflorin, albiflorin and paeoniflorin are three representative monoterpene glycosides in Radix Paeoniae Alba, a well-known traditional Chinese medicine with a great important biological activity.Benzoylpaeoniflorin is a potential therapeutic agent against oxidative stress related Alzheimer's disease.

InChI:InChI=1/C30H32O12/c1-27-14-29(36)19-12-30(27,28(19,26(41-27)42-29)15-38-24(35)17-10-6-3-7-11-17)40-25-22(33)21(32)20(31)18(39-25)13-37-23(34)16-8-4-2-5-9-16/h2-11,18-22,25-26,31-33,36H,12-15H2,1H3/t18-,19-,20-,21+,22-,25+,26-,27+,28+,29-,30+/m1/s1

Downstream Products

• 99624-67-6 7S-Paeonimetabolin-I