38694-48-3

Basic information

• Product Name: DIETHYLPHOSPHONOBUTANOIC ACID
• Synonyms: DIETHYLPHOSPHONOBUTANOIC ACID;DIETHYL-(3-CARBOXYPROPYL)-PHOSPHONATE;4-(DIETHYLPHOSPHONO)BUTANOIC ACID;4-(Diethylphosphono)butanoic acid, 98 %
• CAS NO: 38694-48-3
• Molecular Formula: C₈H₁₇O₅P
• Molecular Weight: 224.19
• Mol File: 38694-48-3.mol
• Article Data: 8

Chemical Properties

• Melting Point: 62°C
• Boiling Point: 358.7 °C at 760 mmHg
• Flash Point: 170.7 °C
• Appearance: /
• Density: 1.167 g/cm³
• Vapor Pressure: 4.07E-06mmHg at 25°C
• Refractive Index: 1.444
• Sensitive: Hygroscopic
• CAS DataBase Reference: DIETHYLPHOSPHONOBUTANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYLPHOSPHONOBUTANOIC ACID(38694-48-3)
• EPA Substance Registry System: DIETHYLPHOSPHONOBUTANOIC ACID(38694-48-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 38694-48-3(Hazardous Substances Data)

Usage

General Description

DIETHYLPHOSPHONOBUTANOIC ACID, also known as DEPB, is a chemical compound with the molecular formula C10H19O3P. It is an organophosphorus compound with potential use as a biochemical research tool. DEPB is a phosphonic acid derivative, and its structure consists of a four-carbon chain with a phosphonate group and two ethyl groups attached. DIETHYLPHOSPHONOBUTANOIC ACID has been studied for its potential use in inhibiting enzyme activity and as a potential precursor for the synthesis of pharmacologically active compounds. Additionally, it may also have applications in the field of agrochemicals and pharmaceuticals due to its unique chemical properties. Overall, DIETHYLPHOSPHONOBUTANOIC ACID has the potential to be used for a variety of research and industrial applications.

InChI:InChI=1/C8H17O5P/c1-3-12-14(11,13-4-2)7-5-6-8(9)10/h3-7H2,1-2H3,(H,9,10)

Upstream product

• 2327-69-7 ethyl 4-(diethoxyphosphoryl)butanoate 
• 96-48-0 4-butanolide 
• 762-04-9 phosphonic acid diethyl ester 
• 64-18-6 formic acid 
• 1067-87-4 Diethyl allylphosphonate 

Downstream Products

• 848487-21-8 (S)-2-{(4E,8E)-2-[2-(Diethoxy-phosphoryl)-ethyl]-5,9,13-trimethyl-tetradeca-4,8,12-trienoylamino}-3-phenyl-propionic acid 
• 247229-69-2 diethyl 3-[N-[5-chloro-2-(N-methylcarbamoyl)phenyl]carbamoyl]propylphosphonate 
• 63075-64-9 diethyl (4-hydroxybutyl)phosphonate 
• 2327-75-5 benzyl 4-(diethoxyphosphoryl)butanoate 

Relevant articles and documents

Pd-Catalyzed Highly Chemo- And Regioselective Hydrocarboxylation of Terminal Alkyl Olefins with Formic Acid

An efficient Pd-catalyzed hydrocarboxylation of alkenes with HCOOH is described. A wide variety of linear carboxylic acids bearing various functional groups can be obtained with excellent chemo- and regioselectivities under mild reaction conditions. The reaction process is operationally simple and requires no handling of toxic CO.

Double prodrugs of a fosmidomycin surrogate as antimalarial and antitubercular agents

A series of eleven double prodrug derivatives of a fosmidomycin surrogate were synthesized and investigated for their ability to inhibit in vitro growth of P. falciparum and M. tuberculosis. A pivaloyloxymethyl (POM) phosphonate prodrug modification was c

NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL ANTI-DIABETIC AGENTS

Novel compounds of the structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK- activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.