388078-30-6

Basic information

• Product Name: Acetamide, 2-chloro-N-(4-fluorophenyl)-N-methyl-
• CAS NO: 388078-30-6
• Molecular Formula: C9H9ClFNO
• Molecular Weight: 201.628
• Mol File: 388078-30-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Acetamide, 2-chloro-N-(4-fluorophenyl)-N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2-chloro-N-(4-fluorophenyl)-N-methyl-(388078-30-6)
• EPA Substance Registry System: Acetamide, 2-chloro-N-(4-fluorophenyl)-N-methyl-(388078-30-6)

Safety Data

• Hazardous Substances Data: 388078-30-6(Hazardous Substances Data)

Upstream product

• 937-25-7 N-(4-fluorophenyl)-N-(methyl)nitrous amide 
• 459-59-6 4-fluoro-N-methylaniline 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 1490436-00-4 C₁₅H₁₂FN₃OS 
• 41192-31-8 5-fluoro-2,3-dihydro-1-methylindol-2-one 
• 388078-34-0 1-methyl-5-fluoroindoline 

Relevant articles and documents

AMP-ACTIVATED PROTEIN KINASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME

The present disclosure relates to compounds of Formula (I): (I); stereoisomers thereof, prodrugs thereof, and pharmaceutically acceptable salts thereof. The present disclosure also relates to uses of the compounds, e.g., to inhibit AMP-Activated protein kinase (AMPK) and treat cancer in a subject.

ACETAMIDO DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS

Disclosed herein are certain acetamido derivatives that are DNA Polymerase Theta (Polθ) inhibitors of Formula (I). Also, disclosed are pharmaceutical compositions comprising such compounds and methods of treating diseases treatable by inhibition of Polθ such as cancer, including homologous recombination (HR) deficient cancers.