38972-84-8 Usage
General Description
2',3',5'-Triacetylinosine is a chemical compound that belongs to the class of organic compounds known as pyrimidone ribonucleosides and ribonucleotides. This class is characterized by compounds containing a pyrimidone base, like uracil or thymine, attached to a ribose or deoxyribose sugar moiety. It is a synthetic derivative of inosine, a naturally occurring purine nucleoside. In 2',3',5'-Triacetylinosine, the hydroxyl groups at the 2', 3', and 5' positions of the ribose sugar are acetylated. Thus, its structure confers unique properties that can contribute to its potential use in various biochemical and pharmacological applications, such as being a precursor in the synthesis of certain nucleosides or serving as an experimental compound in nucleic acid research.
Check Digit Verification of cas no
The CAS Registry Mumber 38972-84-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,9,7 and 2 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 38972-84:
(7*3)+(6*8)+(5*9)+(4*7)+(3*2)+(2*8)+(1*4)=168
168 % 10 = 8
So 38972-84-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H18N4O5/c21-14(20-13(15(22)23)6-12-7-17-10-19-12)8-18-16(24)25-9-11-4-2-1-3-5-11/h1-5,7,10,13H,6,8-9H2,(H,17,19)(H,18,24)(H,20,21)(H,22,23)
38972-84-8Relevant articles and documents
Protease-catalysed synthesis of peptides containing histidine and lysine
Beck-Piotraschke, Karin,Jakubke, Hans-Dieter
, p. 1505 - 1518 (2007/10/03)
The kinetically controlled α-chymotrypsin- and trypsin-catalysed syntheses of peptides starting from simple acyl donor esters containing histidine at the P1-position (nomenclature according to Schechter and Berger) and lysine derivatives as amino components were examined on the basis of their kinetic parameters. Despite higher specificity constants (k(cat)/K(M)) of trypsin-catalysed ester hydrolysis, α-chymotrypsin- catalysed acyl transfer to N(ε)unprotected lysine derivatives gave higher peptide yields as compared to trypsin-catalysed reactions, whereas in acyl transfer to N(ε)-protected lysine derivatives the trypsin-catalysed reaction gave higher yields. α-Chymotrypsin-catalysed acyl transfer reactions in frozen systems demonstrated the yield-enhancing effect of freezing. Using specific ester leaving groups, both the amount of enzyme and the reaction time can be reduced. In frozen systems the ε-amino function of H-Lys-OH acts as an acyl acceptor at pH ≤9.
