390406-53-8 Usage
Chemical Class
Pyrrolidine derivatives
Physical State
White solid
Molecular Weight
330.24 g/mol (calculated from the molecular formula)
Appearance
White crystalline solid
Melting Point
Not provided, but typically pyrrolidine derivatives have a defined melting point
Solubility
Not provided, but generally soluble in organic solvents like methanol, ethanol, or acetone
Stability
Stable under normal conditions, but sensitive to heat, light, and moisture
Reactivity
Reacts with various reagents in organic synthesis
Synthesis
Often used as a building block for the preparation of pharmaceuticals and agrochemicals
Applications
Under active research and development for potential drug candidates for various medical conditions
Safety
Handle with care, as the safety profile is not provided in the material
Storage
Store in a cool, dry place, away from heat, light, and moisture
Regulatory Status
Not provided, but may be subject to specific regulations depending on the intended use and location
Environmental Impact
Not provided, but should be considered when handling and disposing of the compound
Check Digit Verification of cas no
The CAS Registry Mumber 390406-53-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,0,4,0 and 6 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 390406-53:
(8*3)+(7*9)+(6*0)+(5*4)+(4*0)+(3*6)+(2*5)+(1*3)=138
138 % 10 = 8
So 390406-53-8 is a valid CAS Registry Number.
390406-53-8Relevant articles and documents
DISUBSTITUTED PHENYLPYRROLIDINES AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION
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Page/Page column 26, (2010/08/03)
The present invention relates to the use of compounds which increase extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically to the use of 3-disubstituted phenyl-1-pyrrolidinols for the treatment of central nervous system disorders.
Discovery and initial structure-activity relationships of trisubstituted ureas as thrombin receptor (PAR-1) antagonists
Barrow, James C,Nantermet, Philippe G,Selnick, Harold G,Glass, Kristen L,Ngo, Phung L,Young, Mary Beth,Pellicore, Janetta M,Breslin, Michael J,Hutchinson, John H,Freidinger, Roger M,Condra, Cindra,Karczewski, Jerzy,Bednar, Rodney A,Gaul, Stanley L,Stern, Andrew,Gould, Robert,Connolly, Thomas M
, p. 2691 - 2696 (2007/10/03)
Thrombin is the most potent agonist of platelet activation, and its effects are predominantly mediated by platelet thrombin receptors. Therefore, antagonists of the thrombin receptor have potential utility for the treatment of thrombotic disorders. Screening of combinatorial libraries revealed 2 to be a potent antagonist of the thrombin receptor. Modifications of this structure produced 11k, which inhibits thrombin receptor stimulated secretion and aggregation of platelets.
