3908-48-3Relevant articles and documents
Development of non-enzymatic strip for simple and selective determination of urea in water and biological samples
Abbaspour,Norouz-Sarvestani,Mirahmadi
, p. 383 - 388 (2012)
A simple and selective method for the determination of urea based on the paptode technique is described. The sensor was constructed by immobilizing an ionophore on a TLC strip. The procedure is based on the nucleophilic displacement of urea with tetrachlorop-benzoquinone (chloranil) as an ionophore, and the formed violet-color product was detected using a flatbed scanner. The color of each spot was analyzed to red (R), green (G) and blue (B) values from 0 to 255 using a program written in visual basic (VB) programming language. The calibration graph obtained with the proposed sensor was linear over the range of 0.05-10.00 mg L-1 with a detection limit of 0.01 mg L-1 for urea. Parameters such as pH and concentration of chloranil were optimized. The proposed sensor was successfully applied for the determination of urea in bovine serum, urine and tap water samples.
Method for synthesizing 2,5-diaminohydroquinone dihydrochloride
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Paragraph 0024-0028; 0036; 0037; 0039; 0040; 0042; 0043, (2019/04/26)
The invention discloses a method for synthesizing 2,5-diaminohydroquinone dihydrochloride. The method for synthesizing 2,5-diaminohydroquinone dihydrochloride includes the steps that under normal temperature, raw materials including chloranil and a reaction solvent are added into a reaction container, stirring is conducted, ammonium hydroxide is dropwise added, after dropwise addition is completed, temperature is increased to 50-80 DEG C, an ammonolysis reaction is conducted for 2-8 h, then reaction liquid is subjected to after-treatment, and finally an intermediate which is 2,5-diamino-3,6- dichloro-benzoquinone is obtained; 2,5-diamino-3,6-dichloro-benzoquinone, water and Pd/C are added into a reaction kettle for a reduction reaction for 1-8 h at the temperature of 40-80 DEG C and underhydrogen pressure of 0.1-0.6 MPa, then reaction liquid is subjected to after-treatment, and finally the 2,5-diaminohydroquinone dihydrochloride is obtained. Reaction technology parameters are easy tocontrol, energy consumption is low, no toxic side products are generated, the yield is good, purity is high, and industrial feasibility is high.
An efficient synthesis of 2,6-disubstituted benzobisoxazoles: New building blocks for organic semiconductors
Mike, Jared F.,Makowski, Andrew J.,Jeffries-El, Malika
supporting information; experimental part, p. 4915 - 4918 (2009/05/31)
(Chemical Equation Presented) 2,6-Disubstituted benzobisoxazoles have been synthesized by a highly efficient reaction of diaminobenzene diols with various orthoesters. The scope of this new reaction for the synthesis of substituted benzobisoxazoles has been investigated using four different orthoesters. The utility of these compounds as building blocks for the synthesis of conjugated polymers is demonstrated.