391200-05-8

Basic information

• Product Name: Benzonitrile, 5-bromo-2-(methylthio)-
• CAS NO: 391200-05-8
• Molecular Formula: C8H6BrNS
• Molecular Weight: 228.112
• Mol File: 391200-05-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 5-bromo-2-(methylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 5-bromo-2-(methylthio)-(391200-05-8)
• EPA Substance Registry System: Benzonitrile, 5-bromo-2-(methylthio)-(391200-05-8)

Safety Data

• Hazardous Substances Data: 391200-05-8(Hazardous Substances Data)

Upstream product

• 179897-89-3 5-Bromo-2-fluoro-benzonitrile 
• 5188-07-8 sodium thiomethoxide 
• 6609-54-7 2-cyanothioanisole 

Relevant articles and documents

SUBSTITUTED BICYCLIC 1-CARBOXYLIC-ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C

This invention relates to bicyclic 1-carboxylic-acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and their use in methods of treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.

SUBSTITUTED 2-AZA-BICYCLO[2.2.2]OCTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C

This invention relates to 2-Aza-bicyclo[2.2.2]octane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. asthma and allergic diseases, gastrointestinal inflammatory diseases, eosinophilic diseases, chronic obstructive pulmonary disease, infection by pathogenic microbes, rheumatoid arthritis or atherosclerosis.

Novel thiophenes and analogues with anthelmintic activity against Haemonchus contortus

A new series of analogues of 4-(4-fluorophenyl)-2-methylthio-thiophene-3- carbonitrile (1) were synthesized and evaluated for their in vitro and in vivo anthelmintic activity against Haemonchus contortus.