39253-43-5

Basic information

• Product Name: N-(4-Methoxyphenyl)-4-methylbenzenamine
• Synonyms: (4-METHOXY-PHENYL)-P-TOLYL-AMINE;N-(4-Methoxyphenyl)-4-methylbenzenamine;4-Methoxy-4'-methyldiphenylamine;4-methoxy-N-4-tolylaniline;(4-Methoxy-phenyl)-p-tolylanMine;N-(4-Methoxyphenyl)-p-tolylamine;4-Methoxy-N-(p-tolyl)aniline;N-(4-Methoxyphenyl)-4-methylbenzemine
• CAS NO: 39253-43-5
• Molecular Formula: C₁₄H₁₅NO
• Molecular Weight: 213.27
• EINECS: 1533716-785-6
• Mol File: 39253-43-5.mol
• Article Data: 94

Chemical Properties

• Melting Point: 82.0 to 86.0 °C
• Boiling Point: 354.944 °C at 760 mmHg
• Flash Point: 143.714 °C
• Appearance: /
• Density: 1.09 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.602
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: N-(4-Methoxyphenyl)-4-methylbenzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-Methoxyphenyl)-4-methylbenzenamine(39253-43-5)
• EPA Substance Registry System: N-(4-Methoxyphenyl)-4-methylbenzenamine(39253-43-5)

Safety Data

• Hazardous Substances Data: 39253-43-5(Hazardous Substances Data)

Usage

General Description

N-(4-Methoxyphenyl)-4-methylbenzenamine is an organic compound, more specifically an aromatic amine. It is composed of a methoxyphenyl group (C6H5OCH3) and a methylbenzenamine group (C6H5NH2), both of which are bound to a central nitrogen atom. It is used primarily in the field of organic synthesis, where it can act as a building block for the production of more complex chemical structures. The compound's properties, like solubility, melting point, and boiling point, are generally defined by the nature of its aromatic rings and the presence of the amine and ether functional groups. Its exact properties and applications can vary greatly depending on the specific structure and configuration of the compound. Safety procedures should always be followed when handling it due to its potential toxicity.

InChI:InChI=1/C14H15NO/c1-11-3-5-12(6-4-11)15-13-7-9-14(16-2)10-8-13/h3-10,15H,1-2H3

Upstream product

• 624-31-7 4-tolyl iodide 
• 696-62-8 para-iodoanisole 
• 623-10-9 N-(4-methylphenyl)hydroxylamine 
• 18649-43-9 4-methoxyphenyllead(IV) triacetate 
• 106-49-0 p-toluidine 
• 3274-12-2 4-methyl-4-(trichloromethyl)cyclohexa-2,5-dien-1-one 
• 104-94-9 4-methoxy-aniline 
• 3076-56-0 p-tolyllead triacetate 
• 100-66-3 methoxybenzene 
• 2101-86-2 p-methylazidobenzene 
• 623-12-1 4-chloromethoxybenzene 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 66107-29-7 4-methoxyphenyl triflate 
• 5720-05-8 4-methylphenylboronic acid 

Downstream Products

• 5234-30-0 glycozoline 
• 5257-08-9 3-methyl-6-hydroxycarbazol 
• 18440-54-5 N-(4-Methylphenyl)-1,4-benzoquinone monoimine 
• 122527-64-4 C₄₀H₃₆N₂O₂ 
• 1357929-92-0 C₄₈H₆₀N₂O₄Si₄ 
• 1357929-95-3 C₅₂H₇₂N₂O₆Si₆ 
• 1357929-84-0 C₈₁H₆₈N₄O₄ 
• 1378973-60-4 (E)-N-(1,3-diphenylallyl)-4-methoxy-N-p-tolylaniline 
• 59919-04-9 4-methoxy-N-methyl-N-(p-tolyl)aniline 

Relevant articles and documents

Transition metals in organic synthesis, part 82.1 First total synthesis of methyl 6-methoxycarbazole-3-carboxylate, glycomaurrol, the anti-TB active micromeline, and the furo[2,3-c]carbazole alkaloid eustifoline-D

The palladium(0)-catalyzed animation followed by palladium(II)-catalyzed oxidative cyclization of the resulting diarylamine provides a short route to a series of 6-oxygenated carbazole alkaloids: glycozoline, 3-formyl-6- methoxycarbazole, methyl 6-methoxy

Visible-Light- And PPh3-Mediated Direct C-N Coupling of Nitroarenes and Boronic Acids at Ambient Temperature

We present here a metal-free, visible-light- and triphenylphosphine-mediated intermolecular, reductive amination between nitroarenes and boronic acids at ambient temperature without any photocatalyst. Mechanistically, a slow reduction of nitroarenes to a nitroso and, finally, a nitrene intermediate occurs that leads to the amination product with concomitant 1,2-aryl/-alkyl migration from a boronate complex. A wide range of nitroarenes underwent C-N coupling with aryl-/alkylboronic acids providing high yields.

Preparation method of secondary aromatic amine

The invention provides a method for preparing secondary aromatic amine by performing a palladium-catalyzed C-N coupling reaction on (pseudo)aryl halide and (pseudo)heterocyclic aryl halide and primary(heterocyclic)aromatic amine. The method is characterized in that an alkali for promoting the reaction is an alkali metal carboxylate or an alkali metal bicarbonate.