39567-17-4Relevant articles and documents
Efficient synthesis of pyrrolo[1,2-: A] quinoxalines catalyzed by a Br?nsted acid through cleavage of C-C bonds
Xie, Caixia,Feng, Lei,Li, Wanli,Ma, Xiaojun,Ma, Xinkun,Liu, Yihan,Ma, Chen
supporting information, p. 8529 - 8535 (2016/09/28)
An efficient and convenient one-pot domino reaction for the direct synthesis of pyrrolo[1,2-a]quinoxalines has been developed. This approach utilizes an imine formation reaction, SEAr reaction and cleavage of C-C bonds catalyzed by a Br?nsted acid. β-Diketones and β-keto esters are both well tolerated to give the corresponding products in moderate to excellent yields.
Kinetic resolution of α-Methylene- β- Hydroxy esters catalyzed by Acyl transfer catalyst An -PIQ
Jiang, Shan-Shan,Xu, Qin-Chang,Zhu, Ming-Yu,Yu, Xingxin,Deng, Wei-Ping
, p. 3159 - 3169 (2015/03/30)
A highly efficient nonenzymatic kinetic resolution of a series of structurally diverse racemic α-methylene-β-hydroxy esters utilizing the acyl transfer catalyst An-PIQ and propionic anhydride is reported. This procedure provides recovered alcohols with extremely high ee's (up to >99%) in reasonable conversions and excellent selectivity factors (S up to 108). Several synthetically important substrates were resolved in gram-scale reactions, and highly optically pure α-methylene-β-hydroxy esters were obtained with excellent S values and good yields.
Development of the titanium-TADDOLate-catalyzed asymmetric fluorination of β-ketoesters
Hintermann, Lukas,Perseghini, Mauro,Togni, Antonio
supporting information; experimental part, p. 1421 - 1435 (2011/12/15)
Titanium-based Lewis acids catalyze the α-fluorination of β-ketoesters by electrophilic N-F-fluorinating reagents. Asymmetric catalysis with TADDOLato-titanium(IV) dichloride (TADDOL = α,α, α',α'-tetraaryl-(1,3-dioxolane-4,5-diyl)-dimethanol) Lewis acids
