3963-45-9 Usage
General Description
Methacycline hydrochloride is a semi-synthetic tetracycline antibiotic used to treat various bacterial infections. It works by inhibiting the growth of bacteria and is effective against a wide range of gram-positive and gram-negative bacteria. Methacycline is commonly prescribed to treat respiratory infections, urinary tract infections, and skin infections, among others. It is typically taken orally and may be given in combination with other antibiotics for more severe infections. Like other tetracyclines, methacycline may cause side effects such as nausea, vomiting, and diarrhea, and it is not recommended for use in children under the age of 8 or during pregnancy.
Check Digit Verification of cas no
The CAS Registry Mumber 3963-45-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,9,6 and 3 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 3963-45:
(6*3)+(5*9)+(4*6)+(3*3)+(2*4)+(1*5)=109
109 % 10 = 9
So 3963-45-9 is a valid CAS Registry Number.
InChI:InChI=1/C22H22N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-6,10,14-15,17,25,27-29,32H,1H2,2-3H3,(H2,23,31);1H
3963-45-9Relevant articles and documents
Sadee et al.
, p. 595,599 (1971)
A synthesis of 7alpha-hydroxyandrost-4-ene-3,17-dione.
Hossain,Kirk,Mitra
, p. 603 - 608,605, 607 (2007/10/12)
The first convenient chemical synthesis of 7alpha-hydroxyandrost-4-ene-3,17-dione is reported. Androsta-4,6-diene3, 17-dione was converted into its 6alpha, 7alpha-epoxy-derivative; reduction of the epoxide with aluminum amalgam gave 7alpha-hydroxyandrost-4-ene-3,17-dione. This reducing agent is more efficient than chromous acetate for the purpose.
3-Keto-7 α,β-loweralkyl-Δ 5-steroids
-
, (2013/12/16)
7(α,β)-Loweralkyl-3-keto-Δ 5 -androstanes and 7(α,β)-loweralkyl-3-keto-Δ 5 -pregnanes having anabolic, androgenic, claudogenic, progestational and anti-progestational properties are prepared by reacting 3-keto-4,6-dienic androstanes and pregnanes with organocopper reagents such as dialkyllithium cuprate. The isomerization of these compounds to yield 7(α,β)-loweralkyl-3-keto-Δ 4 -steroids is also described.
