39630-24-5Relevant articles and documents
Visible-light, metal-free α-amino C(sp3)-H activation through 1,5-hydrogen migration: A concise method for the preparation of bis(indolyl)alkanes
Shaaban, Saad,Roller, Alexander,Maulide, Nuno
, p. 7643 - 7647 (2015)
A photoredox catalytic, metal-free method for C-H functionalization α to amines directly leads to the formation of bis(indolyl)alkane products in good to excellent yields. This transformation hinges on a smooth 1,5-hydrogen migration to an aryl radical in
Synthesis, antimicrobial evaluation, ot-QSAR and mt-QSAR studies of 2-amino benzoic acid derivatives
Mahiwal, Kuldeep,Kumar, Pradeep,Narasimhan, Balasubramanian
, p. 293 - 307 (2012/09/07)
A series of 2-amino benzoic acid derivatives (1-28) were synthesized and evaluated for their in vitro antimicrobial activity against the panel of Gram positive, Gram negative bacterial and fungal strains. The results of antimicrobial studies indicated that, in general, the synthesized compounds were found to be bacteriostatic and fungistatic in action. QSAR studies performed by the development of one target and multi target models indicated that multi-target model was effective in describing the antimicrobial activity as well demonstrated the effect of structural parameters viz. LUMO, 3χv and W on antimicrobial activity of 2-amino benzoic acid derivatives. Springer Science+Business Media, LLC 2010.
Imidazoline derivatives as alpha-1A adrenoceptor ligands
-
Page/Page column 18, (2010/02/11)
Compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof are disclosed. Such compounds are useful in the treatment of Alpha-1A mediated diseases or conditions such as urinary incontinence.