39930-11-5Relevant articles and documents
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Boyer,Wolford
, p. 1053 (1958)
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MODULATORS OF TREX1
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Paragraph 0091, (2021/01/29)
Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositons thereof, which are useful for treating a variety of conditions associated with TREX1.
Molecular structures of dinuclear zinc(II) complexes of chiral tridentate imine and amine ligands: Effect of ligand geometry on diastereoselectivity
Jena, Himanshu Sekhar,Manivannan, Vadivelu
, p. 210 - 219 (2013/02/22)
Racemic mixtures of Schiff bases (L1H and L2H) were reduced to respective amines (L1′H and L2′H). Compounds of composition [Zn 2(L1)2(NCO)2] (1), [Zn(L1)N3] n (2), [Zn2(L2)2(NCO)2] (3), [Zn2(L1′)2(NCO)2] (1′), [Zn 2(L1)2(N3)2]·2DMF (2′·2DMF) and [Zn2(L2′)2(NCO) 2]·DMF (3′·DMF) were synthesized using these ligands, Zn(NO3)2·6H2O and NCO - or N3- ions. Molecular structures of all six compounds have been established. Both imine and amine ligands have N 2O donor set, but coordinate, respectively, in meridional and facial fashions. First four complexes are monochelates and last two are bis-chelates. The Zn2O2 unit in 1-3 has RS combination of imine where as in 1′ has RR(SS) combinations of amine. In 2′ and 3′, zinc(II) bis-chelates have cis,cis,trans-(OP)2(N A)2(NY)2 stereochemistry and cis-(OP)2 disposition further coordinate to tetrahedral zinc. Compound 1′ exhibits 1D hydrogen-bonded polymer by enantioselective H-bonding interaction. In 2′, DMF molecules assemble RR and SS bis-chelates through N-H?O interactions.
