400073-68-9 Usage
Description
Methyl N-Boc-2-oxopiperidine-3-carboxylate is a chemical compound with the molecular formula C11H17NO5. It is a derivative of piperidine, a heterocyclic organic compound. The "N-Boc" in its name refers to the N-tert-butoxycarbonyl protecting group, which is utilized in organic synthesis. Methyl N-Boc-2-oxopiperidine-3-carboxylate is known for its versatile reactivity and functional group compatibility, making it a valuable intermediate in the synthesis of various drugs, bioactive compounds, and other organic molecules.
Uses
Used in Pharmaceutical Industry:
Methyl N-Boc-2-oxopiperidine-3-carboxylate serves as an essential intermediate for the synthesis of a wide range of drugs and bioactive compounds. Its role in the development of new medications is crucial, as it allows for the protection of specific functional groups during the synthesis process, ensuring the successful creation of the desired pharmaceutical products.
Used in Research Laboratories:
In research settings, Methyl N-Boc-2-oxopiperidine-3-carboxylate is employed for the preparation of chemical compounds and the execution of various organic chemistry reactions. Its presence in laboratories facilitates the exploration of new chemical pathways and the discovery of novel compounds with potential applications in medicine, materials science, and other fields.
Used as a Building Block in Organic Synthesis:
Due to its versatile reactivity and compatibility with functional groups, Methyl N-Boc-2-oxopiperidine-3-carboxylate can be used as a building block for the synthesis of other organic molecules. This makes it a valuable component in the creation of complex organic structures, which can be further utilized in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 400073-68-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,0,0,7 and 3 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 400073-68:
(8*4)+(7*0)+(6*0)+(5*0)+(4*7)+(3*3)+(2*6)+(1*8)=89
89 % 10 = 9
So 400073-68-9 is a valid CAS Registry Number.
400073-68-9Relevant articles and documents
Diastereoselective conjugate addition of organocuprates to chiral racemic olefinic amido esters. Formal total synthesis of paroxetine
Cossy, Janine,Mirguet, Olivier,Gomez Pardo, Domingo,Desmurs, Jean-Roger
, p. 475 - 482 (2003)
The diastereoselective conjugate addition of an organocopper reagent to a chiral racemic olefinic amido ester has been used as the key step in a formal total synthesis of paroxetine.
A Unified Strategy for the Synthesis of Difluoromethyl- And Vinylfluoride-Containing Scaffolds
Duchemin, Nicolas,Buccafusca, Roberto,Daumas, Marc,Ferey, Vincent,Arseniyadis, Stellios
supporting information, p. 8205 - 8210 (2019/10/16)
Here, we report a general method for the synthesis of quaternary and tertiary difluoromethylated compounds and their vinylfluoride analogues. The strategy, which relies on a two-step sequence featuring a C-selective electrophilic difluoromethylation and either a palladium-catalyzed decarboxylative protonation or a Krapcho decarboxylation, is practical, scalable, and high yielding. Considering the generality of the method and the attractive properties offered by the difluoromethyl group, this approach provides a valuable tool for late-stage functionalization and drug development.
Model studies on the synthesis of madangamine alkaloids. Assembly of the macrocyclic rings
Proto, Stefano,Amat, Mercedes,Pérez, Maria,Ballette, Roberto,Romagnoli, Federica,Mancinelli, Andrea,Bosch, Joan
experimental part, p. 3916 - 3919 (2012/09/22)
Using simplified model derivatives, the assembly of the macrocyclic rings of madangamines, including the 13- and 14-membered D rings of madangamines C-E, the all-cis-triunsaturated 15-membered D ring of madangamine A, and the (Z,Z)-unsaturated 11-membered E ring common to madangamines A-E, has been studied.
