400822-47-1

Basic information

• Product Name: 2-chloro-5-nitropyrimidine
• Synonyms: 3,5-Dimethyl-4-bromobenzaldehyde
• CAS NO: 400822-47-1
• Molecular Formula: C₉H₉BrO
• Molecular Weight: 213.0712
• Mol File: 400822-47-1.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 279.576°C at 760 mmHg
• Flash Point: 85.701°C
• Appearance: /
• Density: 1.422g/cm³
• Vapor Pressure: 0.004mmHg at 25°C
• Refractive Index: 1.587
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-chloro-5-nitropyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-5-nitropyrimidine(400822-47-1)
• EPA Substance Registry System: 2-chloro-5-nitropyrimidine(400822-47-1)

Safety Data

• Hazardous Substances Data: 400822-47-1(Hazardous Substances Data)

Usage

General Description

2-chloro-5-nitropyrimidine is a chemical compound that consists of a pyrimidine ring with a chlorine atom at the 2 position and a nitro group at the 5 position. It is commonly used as an intermediate in the synthesis of pharmaceutical compounds, agrochemicals, and dyes. The presence of the nitro group makes 2-chloro-5-nitropyrimidine a valuable building block for the production of various nitrogen-containing organic compounds. Its versatile reactivity and wide range of applications make 2-chloro-5-nitropyrimidine an important chemical in the field of organic synthesis. However, it is important to handle this compound with care due to its potential toxic and harmful effects.

InChI:InChI=1/C9H9BrO/c1-6-3-8(5-11)4-7(2)9(6)10/h3-5H,1-2H3

Upstream product

• 100189-84-2 2,5-dibromo-1,3-dimethylbenzene 
• 68-12-2 N,N-dimethyl-formamide 
• 75344-77-3 4-bromo-3,5-dimethyl benzonitrile 
• 576-83-0 2,4,6-trimethylphenyl bromide 

Downstream Products

• 75344-77-3 4-bromo-3,5-dimethyl benzonitrile 
• 400822-49-3 4-bromo-3,5-dimethylbenzaldehyde oxime 
• 910636-36-1 2-(4-bromo-3,5-dimethyl-phenyl)-[1,3]dioxane 
• 113899-82-4 methyl 4-formyl-2,6-dimethylbenzoate 
• 910636-37-2 2-(4-allyl-3,5-dimethyl-phenyl)-[1,3]dioxane 
• 1402448-61-6 2,4,6-tris(3,5-dimethyl-4-bromophenyl)pyridine 
• 1544740-28-4 ethyl 3-(4-bromo-3,5-dimethylphenyl)propanoate 
• 1458654-33-5 4-(4-bromo-3,5-dimethylphenyl)-2-methylbutan-2-ol 
• 1458654-28-8 3-(4-bromo-3,5-dimethylphenyl)propan-1-ol 
• 1458654-38-0 3-(4-bromo-3,5-dimethylphenyl)propyl methanesulfonate 
• 1544740-30-8 4-(4-bromo-3,5-dimethylphenyl)butanenitrile 
• 1544740-31-9 methyl 4-(4-bromo-3,5-dimethylphenyl)butanoate 
• 1544740-32-0 4-(4-bromo-3,5-dimethylphenyl)butan-1-ol 
• 1544740-33-1 4-(4-bromo-3,5-dimethylphenyl)butyl methanesulfonate 

Relevant articles and documents

Effect of the Molecular Conformation on Excitation Energy Transfer in Conformationally Constrained Boryl-BODIPY Dyads

We studied the dual emission characteristics of a series of boryl-BODIPYs (1-6) comprised of triarylborane (TAB) as an energy donor and BODIPY as an energy acceptor. The molecular conformations of dyads 1-6 were systematically tuned by judiciously changing the spacer that bridged the boryl and BODIPY moieties. Frontier molecular orbitals (FMOs) are localized in 3, 4, and 6 with a twisted molecular conformation. In contrast, FMOs are significantly delocalized in 1, 2, and 5 with the least-twisted molecular conformation. Dyads 1-6 showed dual emission features when they were excited at the TAB-dominated absorption band. However, the ratio between the two emission bands in 1-6 significantly varied depending on the molecular conformations. Systematic photoluminescence (PL) studies (both steady-state and time-resolved PL) together with computational, crystal structure, and anion binding studies established that the frustrated excited-state energy transfer from borane to BODIPY is the cause of the dual emission features in these molecular dyads. These studies also revealed that the energy transfer from borane to BODIPY can be elegantly tuned by modulating the dihedral angle between these two moieties.

Oxidation of Iodo- and Bromo-Substituted Polymethylbenzenes in the System PbO2–CF3COOH–CH2Cl2

The oxidation of mono- and diiodo- and -bromo-substituted polymethylbenzenes (mesitylene and durene) in the system PbO2–CF3COOH–CH2Cl2 at room temperature (2–70 h) leads mainly to the formation of iodo- and brom

QUINAZOLINE DERIVATIVES USED TO TREAT HIV

Described herein are compounds of Formula (I) and tautomers and pharmaceutical salts thereof, compositions and formulations containing such compounds, and methods of using and making such compounds.