401515-97-7

Basic information

• Product Name: 2-Pyridinemethanol,formate(ester)(9CI)
• Synonyms: 2-Pyridinemethanol,formate(ester)(9CI)
• CAS NO: 401515-97-7
• Molecular Formula: C₇H₇NO₂
• Molecular Weight: 137.14
• Product Categories: PYRIDINE
• Mol File: 401515-97-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 216.4±15.0 °C(Predicted)
• Appearance: /
• Density: 1.150±0.06 g/cm3(Predicted)
• PKA: 3.48±0.12(Predicted)
• CAS DataBase Reference: 2-Pyridinemethanol,formate(ester)(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinemethanol,formate(ester)(9CI)(401515-97-7)
• EPA Substance Registry System: 2-Pyridinemethanol,formate(ester)(9CI)(401515-97-7)

Safety Data

• Hazardous Substances Data: 401515-97-7(Hazardous Substances Data)

Upstream product

• 586-98-1 2-Hydroxymethylpyridine 
• 2258-42-6 formyl acetic anhydride 
• 64-18-6 formic acid 
• 401516-10-7 cyclohexanecarboxylic acid 2-pyridinylmethyl ester 

Downstream Products

• 346608-06-8 α-methylbenzeneacetic acid 2-pyridinylmethyl ester 
• 346608-05-7 3-phenylpropionic acid 2-pyridinylmethyl ester 
• 401516-10-7 cyclohexanecarboxylic acid 2-pyridinylmethyl ester 
• 66310-15-4 pyridin-2-ylmethyl benzoate 
• 70415-70-2 pyridin-2-ylmethyl 4-methylbenzoate 
• 70415-72-4 4-methoxybenzoic acid 2-pyridinylmethyl ester 
• 133788-00-8 6-phenyl-3a,4-dihydro-1H-cyclopenta[c]furan-5(3H)-one 

Relevant articles and documents

Method for preparing formate-type compound

The invention discloses a method for preparing a formate-type compound. The method comprises the following steps of: adopting an alcohol-type compound and 1,3-dihydroxyacetone as reaction raw materials, and under the existence of a composite catalyst and an oxidant, reacting for 2-48 hours in a reaction medium in a reactor at a reaction temperature of 25-100 DEG C so as to obtain the formate-typecompound. The method disclosed by the invention is simple, and is mild in reaction condition, and by the method, a target product can be obtained by low cost and high yield; the used catalyst has highcatalytic activity, and is easily separated from a reaction system to be repeatedly used; the whole process is environment-friendly, and the reaction raw material (1,3-dihydroxyacetone) is easily converted from a side product (glycerol) of biodiesel, so that the utilization of the glycerol is promoted.

Silica triflate as an efficient reagent for the chemoselective formylation of alcohols

Silica triflate, as a new and stable silica-based reagent, is prepared by a reaction of silica gel with trifluoromethane sulfonyl chloride at room temperature. This reagent can be used for the efficient and selective formylation of alcohols in the presence of phenols in a relatively short reaction time and high yields under heterogeneous reaction conditions.

Investigations of the scope and mechanism of the tandem hydroesterification/lactonization reaction

(Chemical Equation Presented) Heating allylic and homoallylic alcohols and 2-pyridylmethyl formate in the presence of Ru3(CO)12 initiates a tandem sequence of hydroesterification and lactonization. Mechanistic studies suggest that regioselectivity and overall reaction efficiency are governed by the relative rates of reductive elimination and β-hydride elimination for the alkylruthenium intermediates.