4026-27-1

Basic information

• Product Name: 1,2,3,4-DI-O-ISOPROPYLIDENE-ALPHA-D-FUCOPYRANOSE
• Synonyms: 6-DEOXY-1:2,3:4-DI-O-ISOPROPYLIDENE-ALPHA-D-GALACTOPYRANOSE;1,2,3,4-DI-O-ISOPROPYLIDENE-ALPHA-D-FUCOPYRANOSE;1,2,3,4-DI-O-ISOPROPYLIDENE-ALPHA-D-FUCOSE;1:2,3:4-DI-O-ISOPROPYLIDENE-ALPHA-D-FUCOSE;6-Deoxy-1,2:3,4-di-o-isopropylidene-alpha-D-galactopyranoside;1,2,3,4-Di-O-isopropylidene-a-D-fucopyranose;6-Deoxy-1,2:3,4-di-O-isopropylidene-α-D-galactopyranoside;1,2,3,4-Diisopropylidene-a-D-Fucopyranose
• CAS NO: 4026-27-1
• Molecular Formula: C₁₂H₂₀O₅
• Molecular Weight: 244.28
• Mol File: 4026-27-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 285.665 °C at 760 mmHg
• Flash Point: 108.939 °C
• Appearance: /
• Density: 1.076 g/cm³
• CAS DataBase Reference: 1,2,3,4-DI-O-ISOPROPYLIDENE-ALPHA-D-FUCOPYRANOSE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,4-DI-O-ISOPROPYLIDENE-ALPHA-D-FUCOPYRANOSE(4026-27-1)
• EPA Substance Registry System: 1,2,3,4-DI-O-ISOPROPYLIDENE-ALPHA-D-FUCOPYRANOSE(4026-27-1)

Safety Data

• Hazardous Substances Data: 4026-27-1(Hazardous Substances Data)

Usage

Description

1,2,3,4-Di-O-isopropylidene-alpha-D-fucopyranose is a chemical compound derived from fucopyranose, a type of sugar found in various biological systems. It is characterized by its unique structure, which includes two isopropyl groups and four oxygen atoms bonded to the carbon atoms in the molecule. 1,2,3,4-DI-O-ISOPROPYLIDENE-ALPHA-D-FUCOPYRANOSE is known for its potential applications in the synthesis of various compounds and its ability to serve as a substrate for specific enzymes.

Uses

Used in Pharmaceutical Industry:
1,2,3,4-Di-O-isopropylidene-alpha-D-fucopyranose is used as a potential compound for the synthesis of novel enzyme substrates, specifically for beta-D-fucosidase. This enzyme plays a crucial role in the metabolism of fucosylated compounds, which are involved in various biological processes, including cell signaling and adhesion. By providing a novel substrate for beta-D-fucosidase, this compound can help researchers better understand the enzyme's function and potentially develop new therapeutic strategies for related conditions.
Additionally, this compound may also be used in the development of new drugs targeting fucosylated compounds or in the creation of advanced drug delivery systems that can specifically target cells with fucosylated molecules on their surface. This could have significant implications for the treatment of various diseases, including cancer, by allowing for more targeted and effective therapies.

Upstream product

• 91-22-5 quinoline 
• 4026-28-2 1,2:3,4-di-O-isopropylidene-6-iodo-D-galactopyranose 
• 75717-36-1 ethyl (Z)-3-(phenylsulfanyl)propenoate 
• 94-36-0 dibenzoyl peroxide 
• 79233-84-4 6-O-(imidazolylthiocarbonyl)-1,2:3,4-di-O-isopropylidene-α-D-galactopyranose 
• 4148-55-4 (-)-1,2:3,4-di-O-isopropylidene-6-O-methylsulfonyl-α-D-galactopyranose 
• 4478-43-7 (1,2:3,4-di-O-isopropylidene-6-O-(p-toluensulfonate))-D-galactopiranose 

Downstream Products

• 1128-40-1 methyl α-D-fucopyranoside 
• 3615-37-0 D-Fucose 
• 433717-85-2 p-tolyl 3,4-O-isopropylidene-6-deoxy-1-thio-β-D-galactopyranoside 
• 433717-84-1 p-tolyl 2,3,4-tri-O-acetyl-6-deoxy-1-thio-β-D-galactopyranoside 
• 5158-64-5 2,3,4-tri-O-acetyl-D-fucopyranosyl bromide 
• 155485-70-4 1,2-O-<1-(exo-Cyano)ethylidene>-α-D-fucopyranose 
• 155485-71-5 1,2-O-<1-(exo-Cyano)ethylidene>-3-O-trityl-α-D-fucopyranose 
• 155485-72-6 4-O-Acetyl-1,2-O-<1-(exo-cyano)ethylidene>-3-O-trityl-α-D-fucopyranose 
• 129171-96-6 methyl 3,4-O-benzylidene-6-deoxy-D-galactopyranoside 
• 119824-72-5 C₂₁H₂₁⁽²⁾HO₆ 
• 1220051-61-5 2-azidoethyl (2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-(1->2)-3,4-O-isopropylidene-α-D-fucopyranoside 
• 1220051-64-8 2-azidoethyl (2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-(1->2)-4-O-acetyl-α-D-fucopyranoside 
• 1220051-66-0 2-azidoethyl (2,3,5,6-tetra-O-acetyl-β-D-galactofuranosyl)-(1->3)-[(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-(1->2)]-4-O-acetyl-α-D-fucopyranoside 
• 28553-11-9 fucose 1-phosphate 

Relevant articles and documents

Reactivity of Carbohydrate Radicals Derived from Iodo Sugars and Dibenzoyl Peroxide. Homolytic Heteroaromatic and Aromatic Substitution, Reduction, and Oxidation

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Some Studies on Proximal Addition-Elimination Procedures in Intermolecular Carbon-Carbon Bond-forming Free Radical Reacttions. Convenient Synthesis of Ethyl (E)-(Ethyl 2,3,6,7,8-Pentadeoxy-α-D-erythro-nona-2,7-dienopyranosid)uronate

Et3B-induced hydrostannation of ethyl propiolate with tributyltin hydride afforded a mixture of ethyl (Z)- and (E)-3-(tributyltin)propenoate which, after purification, could be used as such in radical carbon-carbon bond-forming reactions with iodides as t

Synthesis of Deoxy Sugars. Deoxygenation by Treatment with N,N'-Thiocarbonyldiimidazole/Tri-n-butylstannane

Protected sugars containing a free hydroxyl group have been deoxygenated by conversion to the O-(imidazolylthiocarbonyl) derivative with N,N'-thiocarbonyldiimidazole followed by treatment with tri-n-butylstannane.This reaction sequence offers a mild, high-yield procedure for the deoxygenation of hexose derivatives with a hindered secondary hydroxyl group at C-3 or C-4.The primary 6-O-(imidazolylthiocarbonyl) compound obtained from 1,2:3,4-di-O-isopropylidene-α-D-galactopyranose reacts with tri-n-butylstannane to give a mixture of the 6-deoxy sugar (31percent) and starting alcohol (57percent).