402960-19-4 Usage
Description
(3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide is a tetrapeptide-based compound with an off-white solid appearance. It is characterized by its unique chemical structure, which contributes to its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
(3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide is used as an active pharmaceutical ingredient for the development of antiviral drugs, specifically targeting the inhibition of the hepatitis C virus NS3·4A protease. Its unique structure allows it to interfere with the viral replication process, making it a promising candidate for the treatment of hepatitis C.
Used in Research and Development:
In addition to its pharmaceutical applications, (3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide can also be utilized in research and development for the study of viral proteases and their role in the replication of hepatitis C virus. (3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide can serve as a valuable tool in understanding the mechanisms of viral infection and the development of novel antiviral therapies.
Used in Drug Design and Synthesis:
(3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide's unique structure and properties make it a valuable starting point for the design and synthesis of new antiviral agents. Researchers can use (3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide as a template to create new molecules with improved potency, selectivity, and pharmacokinetic properties, ultimately leading to more effective treatments for hepatitis C and other viral infections.
Check Digit Verification of cas no
The CAS Registry Mumber 402960-19-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,2,9,6 and 0 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 402960-19:
(8*4)+(7*0)+(6*2)+(5*9)+(4*6)+(3*0)+(2*1)+(1*9)=124
124 % 10 = 4
So 402960-19-4 is a valid CAS Registry Number.
402960-19-4Relevant articles and documents
A pulls Swiss Wei intermediates for the synthesis of the new method
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Paragraph 0080-0082, (2017/08/18)
The invention discloses a method for preparing (3S)-3-amino-2-hydroxyl-N-cyclopropylhexanamide. The compound can be used as an important intermediate for preparing telaprevir. According to the invention, ethyl butyrylacetate is used as a starting raw material, and through steps of helogenation, substitution, amination, reduction, hydrolysis, deprotection, resolution and the like, (3S)-3-amino-2-hydroxyl-N-cyclopropylhexanamide is prepared. The method provided by the invention has advantages as follows: raw materials are cheap and easily available; reaction yield is high; and costs are high.
Processes and intermediates
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Page/Page column 40; 41, (2010/11/26)
The invention relates to compounds and processes useful for the preparation of protease inhibitors, particularly serine protease inhibitors. The protease inhibitors are useful for treatment of HCV infections.
