40430-66-8

Basic information

• Product Name: 1-ETHYNYLADAMANTANE
• Synonyms: 1-ETHYNYLADAMANTANE
• CAS NO: 40430-66-8
• Molecular Formula: C₁₂H₁₆
• Molecular Weight: 160.25544
• Mol File: 40430-66-8.mol
• Article Data: 19

Chemical Properties

• Melting Point: 82℃ (methanol )
• Boiling Point: 209.3±7.0℃ (760 Torr)
• Flash Point: 70.1±12.3℃
• Appearance: /
• Density: 1.01±0.1 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Acetone (Slightly), Chloroform (Slightly)
• CAS DataBase Reference: 1-ETHYNYLADAMANTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ETHYNYLADAMANTANE(40430-66-8)
• EPA Substance Registry System: 1-ETHYNYLADAMANTANE(40430-66-8)

Safety Data

• Hazardous Substances Data: 40430-66-8(Hazardous Substances Data)

Usage

General Description

1-Ethylyladamantane, also known as rimantadine, is a chemical compound that belongs to the class of adamantanes. It is a derivative of adamantane with an ethynyl group attached to the carbon atom at the 1-position. Rimantadine is used as an antiviral drug for the treatment and prevention of influenza A virus infections. It works by blocking the action of the viral M2 protein, preventing the virus from entering host cells and replicating. Rimantadine has been found to be effective in reducing the severity and duration of influenza symptoms when taken within 48 hours of symptom onset. It is generally well-tolerated and has a low potential for causing adverse effects when used according to the recommended dosage.

Upstream product

• 91800-98-5 1-(2,2-dibromoethynyl)adamantane 
• 67886-48-0 Phosphoric acid (Z)-1-adamantan-1-yl-2-benzenesulfonyl-vinyl ester diphenyl ester 
• 67886-48-0 Phosphoric acid (Z)-1-adamantan-1-yl-2-benzenesulfonyl-vinyl ester diphenyl ester 
• 768-90-1 1-Adamantyl bromide 
• 67886-63-9 1-(1-Adamantyl)-1-(diethoxyphosphinyl)-oxyethen 
• 828-51-3 1-Adamantanecarboxylic acid 
• 1660-04-4 1-acetyladamantane 
• 67886-39-9 1-(1-adamant-1-yl)-2-phenylsulfonylethanone 
• 23074-42-2 1-adamantanecarbonitrile 
• 2094-72-6 1-Adamantanecarbonyl chloride 
• 67886-57-1 1-Amino-1-(1-adamantyl)-2-phenylsulfonylethen 
• 2094-74-8 1-Adamantanecarbaldehyde 
• 90965-06-3 dimethyl 1-(1-diazo-2-oxopropyl)phosphonate 
• 768-92-3 1-adamantyl fluoride 

Downstream Products

• 101698-55-9 1-Oxo-1--3,3-diphenyl-propen-(2) 
• 106386-45-2 1-adamantylpropiolic acid 
• 1660-04-4 1-acetyladamantane 
• 55361-18-7 5-adamantan-1-yl-3-phenyl-isoxazole 
• 55361-19-8 5-adamantan-1-yl-3-(4-nitro-phenyl)-isoxazole 
• 475586-22-2 (S)-3-adamantyl-1-phenyl-(E)-prop-2-en-1-ol 
• 475586-29-9 (S)-N-(1-adamantyl-3-phenyl-(E)-allyl)-2,2,2-trichloro-acetamide 
• 475586-46-0 (S)-(1-adamantyl-3-phenyl-allyl)-carbamic acid benzyl ester 
• 73213-43-1 p-nitrophenyl 1-adamantylpropiolate 
• 187461-69-4 Adamantan-1-yl-propynoic acid 4'-tert-butyl-3-nitro-biphenyl-4-yl ester 
• 922497-19-6 1-{[4-(difluoromethoxy)phenyl]ethynyl}adamantane 
• 425380-83-2 trans-[Fe(1,2-dimethylphosphinoethane)2(C₂-adamantyl)(C₂C₆H₄OCH₃)] 

Relevant articles and documents

PREPARATION OF 1,3-DIALKYNYLADAMANTANES AND THEIR ALUMINIUM BROMIDE-MEDIATED CYCLOADDITION ADDUCTS

The synthesis of 1,3-diethynyl- (1) and 1,3-di(1-propynyl)adamantane (2)is reported.The aluminium bromide induced cocyclodimerization of 2 with propyne affords the dinuclear ? complex 7, and the cyclodimerization of 1 the polynuclear ? complex 8.

Clickable azide-functionalized bromoarylaldehydes – synthesis and photophysical characterization

Herein, we present a facile synthesis of three azide-functionalized fluorophores and their covalent attachment as triazoles in Huisgen-type cycloadditions with model alkynes. Besides two ortho- and para-bromo-substituted benzaldehydes, the azide functionalization of a fluorene-based structure will be presented. The copper(I)-catalyzed azide–alkyne cycloaddition (CuAAC) of the so-synthesized azide-functionalized bromocarbaldehydes with terminal alkynes, exhibiting different degrees of steric demand, was performed in high efficiency. Finally, we investigated the photophysical properties of the azide-functionalized arenes and their covalently linked triazole derivatives to gain deeper insight towards the effect of these covalent linkers on the emission behavior.

METAL ION-INCLUDING FULLERENE DERIVATIVE AND METHOD FOR PRODUCING THE SAME

PROBLEM TO BE SOLVED: To provide a metal ion-including fullerene derivative having a functional group which can have properties according to a wide range of uses and a method for producing the same. SOLUTION: The present invention provides a metal ion-including fullerene derivative in which a diene compound having a functional group having desired properties is introduced into a metal ion-including fullerene or a salt thereof. The functional group has properties including a dye, a catalyst, photoreactivity, water solubility, and the like. The metal ion-including fullerene derivative is described in claim 1. SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2019,JPOandINPIT