4068-57-9

Basic information

• Product Name: 5-chloro-2-hydroxy-3-iodo-benzoic acid
• Synonyms: 5-chloro-2-hydroxy-3-iodo-benzoic acid
• CAS NO: 4068-57-9
• Molecular Weight: 298.464
• Mol File: 4068-57-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-chloro-2-hydroxy-3-iodo-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2-hydroxy-3-iodo-benzoic acid(4068-57-9)
• EPA Substance Registry System: 5-chloro-2-hydroxy-3-iodo-benzoic acid(4068-57-9)

Safety Data

• Hazardous Substances Data: 4068-57-9(Hazardous Substances Data)

Upstream product

• 321-14-2 5-chloro-2-hydroxybenzoic acid 

Downstream Products

• 183371-93-9 methyl 5-chloro-3-iodo-2-methoxybenzoate 
• 4068-68-2 methyl 5-chloro-2-hydroxy-3-iodobenzoate 

Relevant articles and documents

(Hetero)aryl-bicyclic heteroaryl derivatives, their preparation and their use as protease inhibitors

The present invention provides novel compounds of the Formula (I): A-B, its prodrug forms, or pharmaceutically acceptable salts thereof, wherein A represents a saturated, unsaturated, or a partially unsaturated bicyclic heterocyclic ring structure, and B represents an aryl or a heteroaryl group. Preferred compounds of the present invention comprise a benzimidazole or indole nucleus. The compounds of this invention are inhibitors of serine proteases, Urokinase (uPA), Factor Xa (FXa), and/or Factor VIIa (FVIIa), and have utility as anti cancer agents and/or as anticoagulants for the treatment or prevention of thromboembolic disorders in mammals.

Process for preparing chiral dibenzofurans via intramolecular heck reaction

The present invention is directed to the synthesis of 2-chloro-cis-[5a(S)-9a(S)-(5a,6,7,8,9,9a-hexahydro)]dibenzofuran-4-carboxylic acid by an intramolecular Heck stereospecific synthesis substantially free of undesirable 8-chloro-2,6-methano-2H-3,4,5,6-t