408328-13-2

Basic information

• Product Name: 2,6-DIBROMOBENZOTHIAZOLE
• Synonyms: Benzothiazole, 2,6-dibromo-;2,6-Dibromo-benzothiazole;2,6-dibromobenzo[d]thiazole;2,6-dibroMo-1,3-benzothiazole;2,6-Bibromobenzo[d]thiazole, 97%
• CAS NO: 408328-13-2
• Molecular Formula: C₇H₃Br₂NS
• Molecular Weight: 292.98
• Mol File: 408328-13-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 119-121 °C
• Boiling Point: 352.5 °C at 760 mmHg
• Flash Point: 167 °C
• Appearance: /
• Density: 2.114 g/cm³
• Vapor Pressure: 7.78E-05mmHg at 25°C
• Refractive Index: 1.74
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -0.87±0.10(Predicted)
• CAS DataBase Reference: 2,6-DIBROMOBENZOTHIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DIBROMOBENZOTHIAZOLE(408328-13-2)
• EPA Substance Registry System: 2,6-DIBROMOBENZOTHIAZOLE(408328-13-2)

Safety Data

• Hazardous Substances Data: 408328-13-2(Hazardous Substances Data)

Usage

General Description

2,6-Dibromobenzothiazole is a chemical compound with the molecular formula C7H3Br2NS. It is a brominated benzothiazole derivative and is used in the synthesis of pharmaceuticals and other organic compounds. This chemical is known for its wide range of applications, including its use as an intermediate in the production of rubber accelerators, antioxidants, and vulcanization agents. Its properties make it suitable for a variety of industrial uses, and it is also used in research and development of new organic compounds. 2,6-Dibromobenzothiazole is a valuable addition to the field of organic chemistry and has numerous applications in industry and research.

InChI:InChI=1/C7H3Br2NS/c8-4-1-2-5-6(3-4)11-7(9)10-5/h1-3H

Upstream product

• 15864-32-1 2-amino-6-bromobenzothiazole 
• 95-16-9 1,3-Benzothiazole 
• 106-40-1 4-bromo-aniline 

Downstream Products

• 62266-82-4 6-bromo-1,3-benzothiazol-2(3H)-one 
• 1616589-55-9 5-(2-(cyclopropylamino)benzo[d]thiazol-6-yl)-3-(4-fluorophenylsulfonylamino)-2-methoxybenzamide 

Relevant articles and documents

NOVEL APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS

The present invention relates to inhibitors of apoptosis signal-regulating kinase 1 ("ASK1"), a process for synthesis of the compounds of the present invention, composition comprising the compounds and use of the compounds for inhibition of ASK1.

Discovery of a 6-(pyridin-3-yl)benzo[d]thiazole template for optimization of hedgehog and PI3K/AKT/mTOR dual inhibitors

Abstract Vismodegib is the first FDA approved cancer therapy based on inhibition of aberrant hedgehog signaling. Like most cancer therapies, vismodegib suffered from resistance, even during clinical development. Numerous reports demonstrated that simultan

Combination of 2-methoxy-3-phenylsulfonylaminobenzamide and 2-aminobenzothiazole to discover novel anticancer agents

The fragment of 2-substituted-3-sulfonylaminobenzamide has been proposed to replace the fragment of 2-substituted-3-sulfonylaminopyridine in PI3K and mTOR dual inhibitors to design novel anticancer agents based on bioisostere. The combination of the fragm