408355-23-7

Basic information

• Product Name: 7-BROMO-5-FLUOROINDOLE
• Synonyms: 7-BROMO-5-FLUOROINDOLE;1H-Indole, 7-broMo-5-fluoro-;7-bromo-5-fluoro-1H-indene
• CAS NO: 408355-23-7
• Molecular Formula: C₈H₅BrFN
• Molecular Weight: 214.03
• Mol File: 408355-23-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 20-25°C
• Boiling Point: 315.1 °C at 760 mmHg
• Flash Point: >110℃
• Appearance: /
• Density: 1.75 g/cm³
• Vapor Pressure: 0.000829mmHg at 25°C
• Refractive Index: 1.68
• Storage Temp.: 2-8°C
• Sensitive: Light Sensitive
• CAS DataBase Reference: 7-BROMO-5-FLUOROINDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-BROMO-5-FLUOROINDOLE(408355-23-7)
• EPA Substance Registry System: 7-BROMO-5-FLUOROINDOLE(408355-23-7)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-37/38-41
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 408355-23-7(Hazardous Substances Data)

Usage

Uses

7-Bromo-5-fluoroindole is an HIV-1 attachment inhibitor.

InChI:InChI=1/C8H5BrFN/c9-7-4-6(10)3-5-1-2-11-8(5)7/h1-4,11H

Upstream product

• 700-36-7 2-bromo-4-fluoronitrobenzene 
• 1826-67-1 vinyl magnesium bromide 
• 1073-06-9 3-fluorobromobenzene 
• 1003-98-1 2-bromo-4-fluoroaniline 
• 107-14-2 chloroacetonitrile 
• 107-06-2 1,2-dichloro-ethane 

Downstream Products

• 875305-87-6 5-fluoroindole-7-carboxylic acid 
• 399-52-0 5-fluoro-1H-indole 
• 908600-70-4 5-fluoroindole-4-carboxylic acid 
• 908600-86-2 5-fluoro-1-(triisopropylsilyl)-1H-indole 
• 169674-02-6 4-chloro-5-fluoroindole 
• 1050656-45-5 7-bromo-5-fluoro-1-[4-trifluoromethyl-benzyl]-1H-indole 
• 883500-80-9 5-fluoro-1H-indole-7-carbonitrile 
• 1398757-28-2 C₁₄H₁₄FN 
• 1050656-47-7 5-fluoro-1-[4-trifluoromethyl-benzyl]-1H-indole-7-carboxylic acid 
• 1050656-53-5 4-{1-[({5-fluoro-1-[4-trifluoromethyl-benzyl]-1H-indol-7-yl}carbonyl)amino]cyclopropyl}benzoic acid 
• 1050656-50-2 methyl 4-{1-[({5-fluoro-1-[4-trifluoromethyl-benzyl]-1H-indol-7-yl}carbonyl)amino]cyclopropyl}benzoate 
• 1050656-08-0 potassium 4-{1-[({5-fluoro-1-[4-trifluoromethyl-benzyl]-1H-indol-7-yl}carbonyl)amino]cyclopropyl}benzoate 

Relevant articles and documents

COMPOUNDS

The present invention relates to novel oxadiazole derivatives having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.

INDOLE AND INDOLINE CYCLOPROPYL AMIDE DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS

The invention is directed to indole and indoline cyclopropyl amide derivatives as EP4 receptor antagonists useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis and cancer. Ph

Sulfonamide peri-substituted bicyclics for occlusive artery disease

Acyl sulfonamide, peri-substituted, fused bicyclic ring compounds useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed. The compounds are of the general formula A representative example is: