40886-58-6

Basic information

• Product Name: Benzenepropanoic acid, 4-methoxy-b-oxo-a-(triphenylphosphoranylidene)-, ethyl ester
• CAS NO: 40886-58-6
• Molecular Formula: C30H27O4P
• Molecular Weight: 482.516
• Mol File: 40886-58-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, 4-methoxy-b-oxo-a-(triphenylphosphoranylidene)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, 4-methoxy-b-oxo-a-(triphenylphosphoranylidene)-, ethyl ester(40886-58-6)
• EPA Substance Registry System: Benzenepropanoic acid, 4-methoxy-b-oxo-a-(triphenylphosphoranylidene)-, ethyl ester(40886-58-6)

Safety Data

• Hazardous Substances Data: 40886-58-6(Hazardous Substances Data)

Upstream product

• 100-07-2 4-methoxy-benzoyl chloride 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 

Downstream Products

• 51718-85-5 ethyl 3-(4-methoxyphenyl)propynoate 
• 768-60-5 4-methoxyphenylacetylen 
• 58357-91-8 4-(4-methoxy-phenyl)-3-phenyl-3H-pyridine-2,6-dione 
• 2884-26-6 ethyl 3-(4-methoxyphenyl)-2,3-dioxopropanoate 
• 1082439-99-3 4-(4-methoxyphenyl)-2-phenyl-1H-imidazole-5-carboxamide 
• 1082444-54-9 ethyl 4-(4-methoxyphenyl)-2-phenyl-1H-imidazole-5-carboxylate 

Relevant articles and documents

OXAZOLE TYROSINE KINASE INHIBITORS

The invention provides a compound which is an amide of the formula (1), or a salt, solvate, N-oxide or tautomer thereof; wherein: a is 0 or 1; b is 0 or 1 : provided that the sum of a and b is 0 or 1; T is O or NH Ar1 is a monocyclic or bicyclic 5- to 10-membered aryl or heteroaryl group containing up to 4 heteroatoms selected from O, N and S, and being optionally substituted by one or more substituents R1; Ar2 Js a monocyclic or bicyclic 5- to 10-membered aryl or heteroaryl group containing up to 4 heteroatoms selected from O, N and S and being optionally substituted by one or more substituents R2; and R1 and R2are as defined in the claims. The compounds are inhibitors of kinases and in particular FLT3, FLT4 and Aurora kinases.