40887-65-8

Basic information

• Product Name: Hydrazinecarboxylic acid, 2-(4-methylphenyl)-, ethyl ester
• CAS NO: 40887-65-8
• Molecular Formula: C10H14N2O2
• Molecular Weight: 194.233
• Mol File: 40887-65-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Hydrazinecarboxylic acid, 2-(4-methylphenyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Hydrazinecarboxylic acid, 2-(4-methylphenyl)-, ethyl ester(40887-65-8)
• EPA Substance Registry System: Hydrazinecarboxylic acid, 2-(4-methylphenyl)-, ethyl ester(40887-65-8)

Safety Data

• Hazardous Substances Data: 40887-65-8(Hazardous Substances Data)

Upstream product

• 69343-74-4 ethyl 2-(4-methylphenyl)azocarboxylate 
• 637-60-5 p-tolylhydrazine hydrochloride 
• 541-41-3 chloroformic acid ethyl ester 
• 539-44-6 N-4-methylphenylhydrazine 

Downstream Products

• 69343-74-4 ethyl (E)-2-(p-tolyl)diazene-1-carboxylate 
• 223401-43-2 1-(ethoxycarbonyl)-4-phenyl-2-(4-tolyl)semicarbazide 
• 69343-74-4 ethyl 2-(4-methylphenyl)azocarboxylate 

Relevant articles and documents

Systematic Evaluation of 2-Arylazocarboxylates and 2-Arylazocarboxamides as Mitsunobu Reagents

2-Arylazocarboxylate and 2-arylazocarboxamide derivatives can serve as replacements of typical Mitsunobu reagents such as diethyl azodicarboxylate. A systematic investigation of the reactivity and physical properties of those azo compounds has revealed that they have an excellent ability as Mitsunobu reagents. These reagents show similar or superior reactivity as compared to the known azo reagents and are applicable to the broad scope of substrates. pKa and steric effects of substrates have been investigated, and the limitation of the Mitsunobu reaction can be overcome by choosing suitable reagents from the library of 2-arylazocarboxylate and 2-aryl azocarboxamide derivatives. Convenient recovery of azo reagents is available by one-pot iron-catalyzed aerobic oxidation, for example. SC-DSC analysis of representative 2-arylazocarboxylate and 2-arylazocarboxamide derivatives has shown high thermal stability, indicating that these azo reagents possess lower chemical hazard compared with typical azo reagents.

Cp?Rh(III)-catalyzed electrophilic amination of arylboronic acids with azo compounds for synthesis of arylhydrazides

A [Cp?Rh(iii)]-catalyzed electrophilic amination of arylboronic acids with diethyl azodicarboxylate (DEAD) was developed, and arylhydrazides were produced in excellent yields and selectivity. The analogous amination with the arylazocarboxylates afforded t

N-(Propargyl)diazenecarboxamides for 'click' conjugation and their 1,3-dipolar cycloadditions with azidoalkylamines in the presence of Cu(II)

Propargyl functionalized diazenes 1 were prepared by two different approaches and were examined as alkyne click components in copper-catalyzed azide-alkyne cycloadditions (CuAAC) with 2-(azidomethyl)pyridine 5a and four α-azido-ω-aminoalkanes C2-C5 (5b-e)