40930-49-2

Basic information

• Product Name: 2-Chloro-N-(4-chloro-2-nitro-phenyl)-acetamide
• Synonyms: 2-Chloro-N-(4-chloro-2-nitro-phenyl)-acetamide;2,4'-DICHLORO-2'-NITROACETANILIDE
• CAS NO: 40930-49-2
• Molecular Formula: C₈H₆Cl₂N₂O₃
• Molecular Weight: 249.05
• Mol File: 40930-49-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Chloro-N-(4-chloro-2-nitro-phenyl)-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-N-(4-chloro-2-nitro-phenyl)-acetamide(40930-49-2)
• EPA Substance Registry System: 2-Chloro-N-(4-chloro-2-nitro-phenyl)-acetamide(40930-49-2)

Safety Data

• Hazardous Substances Data: 40930-49-2(Hazardous Substances Data)

Upstream product

• 89-63-4 4-Chloro-2-nitroaniline 
• 79-04-9 chloroacetyl chloride 
• 680579-53-7 3-bromo-butyric acid-(4-chloro-2-nitro-anilide) 

Downstream Products

• 725204-93-3 piperidino-acetic acid-(4-chloro-2-nitro-anilide) 
• 855932-01-3 N-phenyl-glycine-(4-chloro-2-nitro-anilide) 
• 857948-51-7 N,N-diethyl-glycine-(4-chloro-2-nitro-anilide) 
• 97457-59-5 3-Hydroxy-benzo[b]thiophene-2-carboxylic acid (4-chloro-2-nitro-phenyl)-amide 
• 861061-57-6 N-phenyl-glycine-(2-amino-4-chloro-anilide) 
• 2654-09-3 piperidino-acetic acid-(2-amino-4-chloro-anilide) 
• 855933-00-5 N,N-diethyl-glycine-(2-amino-4-chloro-anilide) 
• 1040140-30-4 N-(4-chloro-2-nitrophenyl)-5,6-difluoro-1H-benzimidazole-2-carboxamide 
• 1220043-52-6 C₃₀H₁₈BrCl₃N₆O₃S 
• 1253933-72-0 2-{2-[(2,6-dichlorophenyl)amino]phenylmethyl}-3-{4-[(4-chloro-2-nitrophenyl)amino]oxazol-2-yl}-6-bromoquinazolin-4(3H)-on 
• 1242020-45-6 N-(4-chloro-2-nitrophenyl)-2-morpholino-2-thioxoacetamide 
• 2654-40-2 N-(4-chloro-2-nitrophenyl)-2-morpholinoacetamide 
• 1242020-49-0 N-(4-chloro-2-nitrophenyl)-5H-dibenzo[d,f][1,3]diazepine-6-carboxamide 
• 1242020-52-5 S-methyl 2-(4-chloro-2-nitrophenylamino)-2-oxothioacetate 

Relevant articles and documents

Design, synthesis and biological evaluation of novel thienylpyridyl-and thioether-containing acetamides and their derivatives as pesticidal agents

Referring to the structural information of the “hit” compound A from the reported pharmacophore-based virtual screening, a series of novel thienylpyridyl-and thioether/sulfoxide/ sulfone-containing acetamide derivatives have been designed and synthesized.

Synthesis and antimicrobial evaluations of sulfur inserted fluoro-benzimidazoles

A new series of fluorinated sulfur inserted benzimidazole analogues Za-i were synthesized and characterized. The new compounds were screened for their antimicrobial and antioxidant potential. The synthesized compounds were obtained by multiple step synthesis, initiating from the synthesis of 5-(difluoromethoxy)-1H-benzimidazole-2-thiol X. The compounds Ya-i prepared by reacting differently substituted anilines with chloroacetylchloride and triethylamine in DMF. Finally, the compound X was reacted with different derivatives of 2-chloro-N-phenylacetamide resulting in formation of titled compounds Za-i. The synthesized compounds (Za-Zi) were characterized by spectral analysis viz.1H & 13C NMR, mass spectra, elemental analysis and IR. The in vitro antimicrobial potential against Gram-positive (S. aureus and E. faecalis) and Gram-negative bacterial (E. coli and P.aeruginosa) strains as well as fungi (A. niger and C. albicans) was recorded for the obtained compounds. Some of the compounds exhibited encouraging results (in MIC) against Gram-positive and Gram-negative bacterial strains. These studies thus suggest that the designed sulfur inserted fluoro-benzimidazoles scaffold may serve as new promising template for further amplification as antimicrobial agents.

Synthesis and reactivity of monothiooxamides of the aminonitroarene series

Monothiooxamides containing aminonitrobenzene and aminonitropyridine fragments have been synthesized. A possibility to synthesize thioesters and fused imidazole and diazepine derivatives on their basis has been demonstrated. ; 2009 Springer Science+Busine