40958-82-5

Basic information

• Product Name: 1H-pyrazole, sodium salt
• Synonyms: 1H-pyrazole, sodium salt
• CAS NO: 40958-82-5
• Molecular Formula: C₃H₃N₂Na
• Molecular Weight: 91.06703
• EINECS: 255-164-8
• Mol File: 40958-82-5.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 187°Cat760mmHg
• Flash Point: 87.5°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.887mmHg at 25°C
• CAS DataBase Reference: 1H-pyrazole, sodium salt(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-pyrazole, sodium salt(40958-82-5)
• EPA Substance Registry System: 1H-pyrazole, sodium salt(40958-82-5)

Safety Data

• Hazardous Substances Data: 40958-82-5(Hazardous Substances Data)

Usage

Structure

A one-carbon chain with two nitrogen atoms at positions 1 and 2 on the ring

Common uses

As a precursor in the synthesis of organic compounds, a reagent in chemical reactions, and a catalyst in some chemical reactions

Applications

Pharmaceutical industry for the production of certain drugs, and in the field of organic chemistry for the preparation of heterocyclic compounds

Versatility

Valuable for a range of industries due to its catalytic properties and its use in the synthesis of organic compounds and drug production.

InChI:InChI=1/C3H3N2.Na/c1-2-4-5-3-1;/h1-3H;/q-1;+1

Upstream product

• 288-13-1 NH-pyrazole 
• 56850-91-0 methyl 4-(2-bromoethoxy)benzoate 
• 7646-69-7 sodium hydride 
• 148977-74-6 sodium amidotrihydridoborate 

Downstream Products

• 2406-25-9 di-tert-butyl nitroxide 
• 1028263-43-5 3-Methanesulfonyl-4-pyrazol-1-yl-benzoic acid 
• 190368-11-7 5-Methanesulfonyl-2-methyl-4-pyrazol-1-yl-benzoic acid 
• 317808-26-7 1,2,4,5-tetrakis(pyrazol-1-yl)benzene 
• 120214-43-9 {Ru(CO)2(N₂C₃H₃)(PPh₃)}2 
• 81760-64-7 [(COD)Rh(μ-pyrazolato)2Rh(P(OPh)3)2] 
• 98420-38-3 dicarbonylbis(triphenylphosphine)bis(μ-pyrazolyl)diiridium(I) 
• 92283-13-1 (Ir(CO)(P(C₆H₅)3)(C₃H₃N₂))2*C₆H₁₄ 
• 81274-22-8 Rh(C₃H₃N₂)(CS)(P(C₆H₁₁)3)2 
• 81274-21-7 Rh(C₃H₃N₂)(CS)(P(C₆H₅)3)2 
• 81014-18-8 4,8-bis(dimethylamino)-4,8-diphenylpyrazabole 
• 177562-55-9 Ru₂(CO)4(C₃H₃N₂)(C₃HN₂(CH₃)2)(P(C₆H₅)3)2 
• 1264294-84-9 3-(4-chlorophenyl)-7-(2-methyl-1-phenyl-3-(1H-pyrazol-1-yl)propan-2-yl)pyrazolo[1,5-a]pyrimidine 
• 102-54-5 ferrocene 

Relevant articles and documents

A practical synthetic method of O -(2-(Pyrazol-1-yl)pyridin-5-yl) methylhydroxylamine as a component of modithromycin

A practical synthesis of O-(2-(pyrazol-1-yl)pyridin-5-yl) methylhydroxylamine was achieved from the inexpensive raw materials, 2-chloro-5-chloromethylpyridine, pyrazole, and acetone oxime, using common reagents such as aq NaOH and sulfuric acid.

Br?nsted and Lewis Base Behavior of Sodium Amidotrihydridoborate (NaNH2BH3)

The reactivity of sodium amidoborane (NaNH2BH3) as a Br?nsted and Lewis base was studied systematically. The [NH2BH3]– anion can act as a proton acceptor or a hydride donor in different types of reactions. In reactions with very weak Br?nsted acids such as cyclopentadiene, ammonia, and pyrazole, the [NH2BH3]– anion acts as a proton acceptor through the lone pair on N. The reactions of [NH2BH3]– with stronger Br?nsted acids are complicated. In the reaction with ammonium chloride or acetic acid, [NH2BH3]– accepts a proton, reforming NH3BH3. However, in the reaction with HCl or methanol, N–B bond cleavage occurs. [NH2BH3]– can also donate hydride in some reactions. The possible mechanisms of these reactions are discussed.

Synthesis and characterization of copper(II) complexes incorporating pyrazolyl-derived N,S-donor bidentate ligands

The novel bidentate N,S-donor anionic ligands [PhNCSIndz]-, [PhNCSImz]-, [PhNCSPzMe3]-, and [EtNCSPz]-, where Indz = indazole, Imz = imidazole, PzMe3 = 3,4,5-trimethylpyrazole, and Pz = pyrazole, were synthesized and used