40963-62-0 Usage
Description
[2,3']bipyridinyl-4-ylamine is a chemical compound that features a bipyridine core with an amine functional group at the 4-position. It is widely recognized for its ability to form stable and efficient complexes with various metal ions, which makes it a valuable asset in the realms of catalysis, material science, and medicinal chemistry. Furthermore, [2,3']bipyridinyl-4-ylamine has garnered attention for its potential biological activities, such as antimicrobial and antitumor properties, positioning it as a promising candidate for further exploration in medicinal chemistry.
Uses
Used in Coordination Chemistry:
[2,3']bipyridinyl-4-ylamine is used as a ligand for transition metal complexes in coordination chemistry. Its ability to form stable and efficient complexes with various metal ions makes it a valuable tool for enhancing the properties and performance of these complexes.
Used in Catalysis:
In the field of catalysis, [2,3']bipyridinyl-4-ylamine is employed as a ligand to create transition metal complexes that can act as catalysts. These complexes are known to improve the efficiency and selectivity of various chemical reactions.
Used in Material Science:
[2,3']bipyridinyl-4-ylamine is utilized in material science to develop new materials with enhanced properties. The complexes formed with metal ions can exhibit unique optical, electronic, and magnetic characteristics, making them suitable for a range of applications, such as sensors, solar cells, and light-emitting diodes (LEDs).
Used in Medicinal Chemistry:
In the realm of medicinal chemistry, [2,3']bipyridinyl-4-ylamine is used as a starting point for the development of new drugs. Its potential biological activities, including antimicrobial and antitumor properties, make it an interesting target for the creation of novel therapeutic agents.
Used in Antimicrobial Applications:
[2,3']bipyridinyl-4-ylamine is used as an antimicrobial agent due to its potential to inhibit the growth of various microorganisms. This property can be harnessed in the development of new antibiotics and antifungal agents to combat drug-resistant infections.
Used in Antitumor Applications:
[2,3']bipyridinyl-4-ylamine is used as an antitumor agent in medicinal chemistry. Its potential to exhibit antitumor properties makes it a promising candidate for the development of new cancer treatments, particularly for targeting various types of cancer cells.
Check Digit Verification of cas no
The CAS Registry Mumber 40963-62-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,9,6 and 3 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 40963-62:
(7*4)+(6*0)+(5*9)+(4*6)+(3*3)+(2*6)+(1*2)=120
120 % 10 = 0
So 40963-62-0 is a valid CAS Registry Number.
40963-62-0Relevant articles and documents
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Abdullaev et al.
, (1973)
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Tetraphosphine/palladium-catalyzed Suzuki-Miyaura coupling of heteroaryl halides with 3-pyridine- and 3-thiopheneboronic acid: An efficient catalyst for the formation of biheteroaryls
Wang, Kun,Fu, Qi,Zhou, Rong,Zheng, Xueli,Fu, Haiyan,Chen, Hua,Li, Ruixiang
, p. 232 - 238 (2013/05/08)
An easily prepared tetraphosphine N,N,N′,N′- tetra(diphenylphosphinomethyl)-1,2-ethylenediamine (L1) associated with [Pd(η3-C3H5)Cl]2 affords an efficient catalyst for Suzuki-Miyaura coupling of 3-pyridineboronic acid with heteroaryl bromides. Reaction could be performed with as little as 0.02 mol% catalyst and a high turnover number of 2500 is obtained. A wide range of substrates is investigated with satisfactory yields, and good compatibility with aminogroup-substituted pyridines and unprotected indole is exhibited. This protocol can also be applied successfully to the reaction of heteroaryl bromides with 3-thiopheneboronic acid. This Pd-tetraphosphine catalyst efficiently restrains the poisoning effect from heteroaryls, and shows good stability and longevity. Copyright 2013 John Wiley & Sons, Ltd. An easily prepared tetraphosphine L1 was successfully used in Pd catalyzed Suzuki reaction of heteroaryl bromides with 3-pyridineboronic acid. A high turnover number of 2 500 was achieved and a wide range of heteroaryl halides including aminopyridines and indole was tolerated. With this protocol the coupling of 3-thiopheneboronic acid with heteroaryl bromides could also proceed in good yields. This catalyst system efficiently restrained poisoning effect from heteroaryls, and exhibited good stability and longevity. Copyright
New cyclopentadienyl, indenyl or fluorenyl substituted phosphine compounds and their use in catalytic reactions
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Page/Page column 53; 58; 59, (2008/06/13)
The invention is directed to a phosphine compound represented by general formula (1) wherein R' and R" independently are selected from alkyl, cycloalkyl and 2-furyl radicals, or R' and R" are joined together to form with the phosphorous atom a carbon-phosphorous monocycle comprising at least 3 carbon atoms or a carbon-phosphorous bicycle; the alkyl radicals, cycloalkyl radicals, and carbon-phosphorous monocycle being unsubstituted or substituted by at least one radical selected from the group of alkyl, cycloalkyl, aryl, alkoxy, and aryloxy radicals; Cps is a partially substituted or completely substituted cyclopentadien-1-yl group, including substitutions resulting in a fused ring system, and wherein a substitution at the 1-position of the cyclopentadien-1-yl group is mandatory when the cyclopentadien-1-yl group is not part of a fused ring system or is part of an indenyl group. Also claimed is the use of these phosphines as ligands in catalytic reactions and the preparation of these phosphines.
