4114-31-2 Usage
Description
Ethyl carbazate, also known as N-hydroxyurethane, is an organic compound that serves as a synthetic intermediate in the production of various chemical compounds. It is characterized by its off-white crystalline appearance and is widely utilized in the chemical industry for the synthesis of different products.
Uses
1. Used in Pharmaceutical Industry:
Ethyl carbazate is used as a synthetic intermediate for the preparation of various pharmaceutical compounds. Its ability to react with different reagents makes it a versatile building block in the synthesis of drugs.
2. Used in Chemical Synthesis:
Ethyl carbazate is used as a synthetic intermediate for the preparation of 4-phenylurazole, which can be further oxidized to yield 4-phenyl-1,2,4-triazole-3,5-dione. Ethyl carbazate is essential in the development of various chemical products.
3. Used in Analytical Chemistry:
Ethyl carbazate is used as a synthetic intermediate in the modification of procedures to isolate analytically pure monoalkylhydrazine hydrochlorides in greater than 90% yield, starting from a ketone or aldehyde.
4. Used in Organic Chemistry:
Ethyl carbazate is used in the treatment of primary amines with chloroamine or hydroxylamine-O-sulfonic acid, as well as in the condensation of a carbonyl compound with ethyl carbazate to form various organic compounds.
5. Used in Catalyst Synthesis:
Ethyl carbazate is used in the FeCl3-catalyzed reaction to produce β-hydroxyester in better yield, showcasing its utility in enhancing the efficiency of chemical reactions.
6. Used in Synthesis of 5-aryl-2,4-dihydro-3H-1,2,4-triazol-3-ones:
Ethyl carbazate is used in a one-pot neat synthesis of some 5-aryl-2,4-dihydro-3H-1,2,4-triazol-3-ones through cyclocondensation with aryl nitriles, catalyzed by DMAP as an efficient and basic nucleophilic catalyst. This application highlights its role in the synthesis of complex organic compounds.
Hazard
Irritant.
Purification Methods
Fractionate the carbazate using a Vigreux column (p 11) until the distillate crystallises [Allen & Bell Org Synth Coll Vol III 404 1955, Beilstein 3 IV 174].
Check Digit Verification of cas no
The CAS Registry Mumber 4114-31-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,1 and 4 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4114-31:
(6*4)+(5*1)+(4*1)+(3*4)+(2*3)+(1*1)=52
52 % 10 = 2
So 4114-31-2 is a valid CAS Registry Number.
InChI:InChI=1/C3H8N2O2/c1-2-5(4)3(6)7/h2,4H2,1H3,(H,6,7)/p-1
4114-31-2Relevant articles and documents
On triazoles. XXXIV. The correct structure of the ethoxycarboxylated 5-amino-1H-1,2,4-triazole and its product with hydrazine
Reiter
, p. 745 - 748 (1994)
The structure of the ethoxycarboxylated product of 5-amino-1H-1,2,4-triazole and its hydrazide was corrected using their ir, pmr, cmr and mass spectra.
A METHOD FOR PRODUCING POTASSIUM 1,1 -DINITRAMINO-5,5-BISTETRAZOLATE AND EXPLOSIVE COMPOSITIONS COMPRISING SAID SALT
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Paragraph 0051; 0110, (2020/06/16)
A method of producing K2DNABT wherein a biztetrazole intermediate is nitrated using a nitrating agent selected from the following: dinitronium disulphate; a mixture of nitric acid and sulfuric acid; a mixture of nitric acid and phosphorous pentoxide; and nitric acid with acetic anhydride.
1. 2, 3 - thiadiazole - 5 - a amidine compound synthesis method
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Paragraph 0025; 0046; 0047, (2017/06/13)
The invention discloses a novel method for synthesizing a 1,2,3-thiadiazole-5-formamidine compound. The target compound shown in general formula TDCA is prepared from a compound as shown in general formula M by virtue of a methylation reaction. The target component as shown in the general formula M is prepared from a compound as shown in general formula A and a compound as shown in general formula N by virtue of a condensation reaction, wherein during the methylation reaction, preferably, a catalyst is an organic metallic catalyst consisting of cuprous iodide and a ligand, namely 2,2,6,6-tetramethyl-3,5-heptadione; during the reaction, preferably, dimethylbenzene is taken as a solvent, and the optimum reaction temperature is 100-140 DEG C. The method disclosed by the invention is high in yield and more environment-friendly (as shown in Specification).
