41172-57-0 Usage
Description
Methyl 5-methyl-4-oxazolecarboxylate, also known as 5-Methyl-4-oxazolecarboxylic Acid Methyl Ester, is an organic compound that serves as a versatile reagent in the synthesis of various heterocyclic compounds. It is characterized by its ability to form different types of chemical bonds, making it a valuable component in the creation of complex molecular structures.
Uses
Used in Pharmaceutical Industry:
Methyl 5-methyl-4-oxazolecarboxylate is used as a reagent for the synthesis of various substituted oxazolyl-1,3,4-thiadiazoles, -1,3,4-oxadiazoles, and -1,2,4-triazoles. These compounds are essential in the development of new pharmaceuticals, particularly those with potential applications in the treatment of various diseases and conditions.
Used in Organic Chemistry Research:
In the field of organic chemistry, Methyl 5-methyl-4-oxazolecarboxylate is used as a reagent in the synthesis of complex molecular structures, such as Muscoride A. Methyl 5-methyl-4-oxazolecarboxylate has been studied for its potential biological activities and may hold promise for future drug development.
Overall, Methyl 5-methyl-4-oxazolecarboxylate plays a crucial role in the synthesis of various heterocyclic compounds, which are essential in the pharmaceutical industry and organic chemistry research. Its versatility as a reagent allows for the creation of a wide range of molecular structures with potential applications in drug development and other areas of scientific inquiry.
Check Digit Verification of cas no
The CAS Registry Mumber 41172-57-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,1,7 and 2 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 41172-57:
(7*4)+(6*1)+(5*1)+(4*7)+(3*2)+(2*5)+(1*7)=90
90 % 10 = 0
So 41172-57-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H7NO3/c1-4-5(6(8)9-2)7-3-10-4/h3H,1-2H3
41172-57-0Relevant articles and documents
Method of coupling, and the coupling method using the aromatic group-substituted heterocyclic compound
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Paragraph 0271; 0275-0277; 0303-0305, (2020/09/17)
Provided is an easy method (coupling method) capable of easily synthesizing a compound group in which aromatic molecules and aromatic molecules are coupled, a compound group in which aromatic molecules and alkene molecules are coupled, and the like without producing halogen waste and without the need to use scarce and expensive palladium. A compound (A) shown by general formula (A): Ar-H and a compound (B1) shown by general formula (B1): RaOCO-Ar', a compound (B2) shown by general formula (B2): RbCH=C(Ar")2, or a compound (B3) shown by general formula (B3): RcOCOCH=C(Ar")2 are reacted in the presence of a nickel compound.
Nickel-catalyzed decarboxylative arylation of heteroarenes through sp2 C-H functionalization
Yang, Ke,Wang, Peng,Zhang, Cheng,Kadi, Adnan A.,Fun, Hoong-Kun,Zhang, Yan,Lu, Hongjian
supporting information, p. 7586 - 7589 (2015/04/22)
The direct decarboxylative arylation of hetereoarenes with benzoic acids through a nickel-catalyzed sp2 C-H functionalization process was developed. This process provides the first examples of decarboxylative cross-coupling reactions with aroma
Decarbonylative C-H coupling of azoles and aryl esters: Unprecedented nickel catalysis and application to the synthesis of muscoride A
Amaike, Kazuma,Muto, Kei,Yamaguchi, Junichiro,Itami, Kenichiro
supporting information; experimental part, p. 13573 - 13576 (2012/10/08)
A nickel-catalyzed decarbonylative C-H biaryl coupling of azoles and aryl esters is described. The newly developed catalytic system does not require the use of expensive metal catalysts or silver- or copper-based stoichiometric oxidants. We have successfully applied this new C-H arylation reaction to a convergent formal synthesis of muscoride A.
