4128-37-4Relevant articles and documents
Application of 15N Spectroscopy and Dynamic NMR to the Study of Ureas, Thioureas and their Lewis Acid Adducts
Martin, M. L.,Filleux-Blanchard, M. L.,Martin, G. J.,Webb, G. A.
, p. 396 - 402 (1980)
Rotational barriers and 15N chemical shifts have been measured in a number of ureas and thioureas.As anticipated on the basis of the 15N shifts, several previosly unobserved rotational barriers could be detected by using lanthanide reatgents or a high field spectometer.Nearly constant effects on both the rotational activation energy and the 15N shift are produced on going from ureas to the corresponding thioureas, and correlations are found between the ΔG(ex. cit) and ?15N values.The results are discussed in terms of lone pair delocalization, and anomalies with respect to general behaviour are tentatively explained in the light of the effect of steric torsion in crowded structures on the 15N shifts and rotation barriers.
Not the Alkoxycarbonylamino-acid O-Acylisourea
Benoiton, N. Leo,Chen, Francis M. F.
, p. 543 - 545 (1981)
The reaction of equivalent amounts of N-benzyloxycarbonyl-L-valine and N,N'-di-isopropylcarbodi-imide in deuteriochloroform gives an equimolar mixture of the symmetrical anhydride of the N-protected amino-acid, N,N'-di-isopropylurea, and unchanged carbodi-imide and not the O-acylisourea adduct as reported in the literature.
Aripova et al.
, (1975)
Co-N-doped carbon nanotubes supported on diatomite for highly efficient catalysis oxidative carbonylation of amines with CO and air
Li, Jiangwei,Tu, Dong-huai,Li, Yani,Wang, Weiqiang,Yu, Qinwei,Yang, Jianming,Lu, Jian
, p. 112 - 116 (2017/10/09)
Cobalt-nitrogen-doped carbon nanotubes stably supported on diatomite were obtained by employing Co(OAc)2/phenanthroline. The resulting material was found to be excellent catalysts for the carbonylation of a variety of amines with CO other than phosgene. Both high activity and selectivity were achieved in this carbonylation process, and it allows air as a cheap oxidizing agent. Moreover the catalyst could be recycled for several times with relatively higher activity compared to homogeneous catalyst palladium acetate.
Synthesis of Amides and Phthalimides via a Palladium Catalyzed Aminocarbonylation of Aryl Halides with Formic Acid and Carbodiimides
Seo, Yong-Sik,Kim, Dong-Su,Jun, Chul-Ho
supporting information, p. 3508 - 3512 (2016/12/26)
A novel method for the preparation of amides and phthalimides has been developed. The process involves a palladium catalyzed aminocarbonylation of an aryl halide, using a carbodiimide and formic acid as the carbonyl source. Experimental data suggest that the mechanistic pathway for this process involves in-situ generation of carbon monoxide from the reaction of formic acid with a carbodiimide in the presence of a palladium catalyst. The method can be used to produce a variety of amides and N-substituted phthalimides efficiently.