41340-30-1

Basic information

• Product Name: 4-Chlorotryptophol
• Synonyms: 4-CHLOROTRYPTOPHOL;2-(4-Chloro-1H-indol-3-yl)ethanol;4-CHLOROTRYPTOPHOL, 98+%;4-Chloro-1H-indole-3-ethanol
• CAS NO: 41340-30-1
• Molecular Formula: C10H10ClNO
• Molecular Weight: 195.65
• Mol File: 41340-30-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 390.735 °C at 760 mmHg
• Flash Point: 190.11 °C
• Appearance: /
• Density: 1.357 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.681
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-Chlorotryptophol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chlorotryptophol(41340-30-1)
• EPA Substance Registry System: 4-Chlorotryptophol(41340-30-1)

Safety Data

• Hazardous Substances Data: 41340-30-1(Hazardous Substances Data)

Usage

General Description

4-Chlorotryptophol is a chemical compound that belongs to the tryptophol family, which are derivatives of the amino acid tryptophan. It is a chlorinated tryptophol compound, where a chlorine atom is substituted at the 4th position of the tryptophol molecule. 4-Chlorotryptophol has been studied for its potential biological and pharmaceutical properties, including its role as a neurotransmitter in the central nervous system. Additionally, 4-Chlorotryptophol has been investigated for its potential use in medicinal chemistry, particularly in the development of new drugs for the treatment of various neurological and psychiatric disorders. Its unique structure and properties make it a valuable compound for further research and potential applications in the field of medicine and neuroscience.

InChI:InChI=1/C10H10ClNO/c11-8-1-2-9-7(3-4-13)6-12-10(9)5-8/h1-2,5-6,12-13H,3-4H2

Upstream product

• 57791-14-7 (4-chloro-1H-indol-3-yl)-oxo-acetic acid ethyl ester 

Downstream Products

• 898746-54-8 tert-butyl 4-chloro-3-(2-hydroxyethyl)-1H-indole-1-carboxylate 

Relevant articles and documents

Discovery of pyrano[3,4-b]indoles as potent and selective HCV NS5B polymerase inhibitors

A novel series of HCV NS5B RNA-dependent RNA polymerase inhibitors containing a pyrano-[3,4-b]indole scaffold is described leading to the discovery of compound 16, a highly potent and selective inhibitor that is active in the replicon system.

A novel class of potential antidepressants: 1 aminoalkyl 1,3,4,9 tetrahydropyrano [3,4 b]indoles

A series of twenty four 1,3,4,9 tetrahydropyrano[3,4 b]indoles bearing baic side chains at positions 1 or 9 have been synthesized and their acute toxicities and antidepressant properties have been determined. One of the most active compounds was 1,9 dimethyl 1 [2 (dimethylamino)ethyl] 1,3,4,9 tetrahydropyrano[3,4 b]indole hydrochloride (AY 23,671), having an ED50 of 0.51 mg/kg i.p. in mice in preventing reserpine induced ptosis. The enantiomers of this compound were examined and were found to have the same order of activity as the racemate.