41351-30-8 Usage
Description
2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE, also known as a benzophenone derivative, is an organic compound characterized by its white to off-white powdery appearance. It is a synthetic molecule with a unique chemical structure that features two methoxy groups at the 2nd and 4th positions, and a hydroxy group at the 4'th position on the benzophenone backbone. 2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE is known for its stability and reactivity, making it a versatile building block in various chemical and pharmaceutical applications.
Uses
Used in Pharmaceutical Industry:
2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Chemical Synthesis:
2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE is used as a building block in the synthesis of other organic compounds, particularly in the field of materials science. Its reactivity and stability make it a valuable component in the creation of novel materials with specific properties.
Used in Solid-Phase Peptide Synthesis:
2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE is used as a linker in solid-phase peptide synthesis with the FMOC (9-fluorenylmethoxycarbonyl) strategy. This application takes advantage of the compound's ability to form stable covalent bonds with peptides, facilitating the stepwise assembly of peptide chains on an insoluble resin support. This method is widely used in the production of peptides and proteins for research and therapeutic purposes.
Preparation
Preparation by Friedel–Crafts acylation of resorcinol dimethyl ether with p-hydroxybenzoic acid, ? in the presence of zinc chloride and phosphorous oxychloride at 60–65° for 1.5 h (71%) or in nitrobenzene at 60° for 2–3 h; ? in the presence of polyphosphoric acid.
Check Digit Verification of cas no
The CAS Registry Mumber 41351-30-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,3,5 and 1 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 41351-30:
(7*4)+(6*1)+(5*3)+(4*5)+(3*1)+(2*3)+(1*0)=78
78 % 10 = 8
So 41351-30-8 is a valid CAS Registry Number.
41351-30-8Relevant articles and documents
Synthesis and Antileukemic Activity of Novel 2-(4-(2,4-dimethoxybenzoyl)phenoxy)-1-(4-(3-(piperidin-4-yl)propyl)piperidin-1-yl)ethanone Derivatives
Vinaya, Kambappa,Kavitha, Chandagirikoppal V.,Prasanna, Doddakunche S.,Chandrappa, Siddappa,Ranganatha, Somasagara R.,Raghavan, Sathees C.,Rangappa, Kanchugarakoppal S.
scheme or table, p. 360 - 367 (2012/06/04)
A series of novel 2-(4-(2,4-dimethoxybenzoyl)phenoxy)-1-(4-(3-(piperidin-4-yl)propyl) piperidin-1-yl)ethanone derivatives 9(a-e) and 10(a-g) were synthesized and characterized by 1H NMR, IR, mass spectral, and elemental analysis. These novel co
Synthesis and anti-inflammatory activity of novel (4-hydroxyphenyl)(2,4- dimethoxyphenyl) methanone derivatives
Vinaya, Kambappa,Naika, Raja,Ananda Kumar, Channappillekoppal S.,Ranganath, Somasagara R.,Benaka Prasad, Salekoppal B.,Krishna, Venkatarangaiah,Rangappa, Kanchugarakoppal S.
experimental part, p. 476 - 483 (2009/12/06)
In the scope of the research program aiming to perform the synthesis and pharmacological evaluation of novel possible anti-inflammatory compounds, in this manuscript, we report the synthesis of novel carboxamide 9a-d and thioamide 10a-d derivatives from t
SOLID-PHASE SYNTHESIS OF PROTECTED PEPTIDE FRAGMENTS USING A TRIALKOXY-DIPHENYL-METHYLESTER RESIN
Rink, Hans
, p. 3787 - 3790 (2007/10/02)
A trialkoxy-diphenyl-methylester and amide linkage for solid-phase peptide synthesis with Fmoc strategy is described.Protected peptide esters can be smoothly cleaved with weak acid, resulting in fragments with intact side-chain protection.Mild acidic clea
