41393-49-1

Basic information

• Product Name: Propanedioic acid, [(chloroacetyl)amino][[4-chloro-2-(2-fluorobenzoyl)phenyl]azo]-, diethyl ester
• CAS NO: 41393-49-1
• Molecular Formula: C22H20Cl2FN3O6
• Molecular Weight: 512.322
• Mol File: 41393-49-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, [(chloroacetyl)amino][[4-chloro-2-(2-fluorobenzoyl)phenyl]azo]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, [(chloroacetyl)amino][[4-chloro-2-(2-fluorobenzoyl)phenyl]azo]-, diethyl ester(41393-49-1)
• EPA Substance Registry System: Propanedioic acid, [(chloroacetyl)amino][[4-chloro-2-(2-fluorobenzoyl)phenyl]azo]-, diethyl ester(41393-49-1)

Safety Data

• Hazardous Substances Data: 41393-49-1(Hazardous Substances Data)

Upstream product

• 41394-71-2 2-(chloroacetylamino)propanedioic acid diethyl ester 
• 784-38-3 2-amino-5-chloro-2'-fluorobenzophenone 

Downstream Products

• 40408-69-3 1-[4-chloro-2-(2-fluorobenzoyl)phenyl]-5-(chloromethyl)-1,2,4-triazole-3-carboxylic acid 
• 40408-66-0 8-chloro-6-(2-fluorophenyl)-4H-[1,2,4]triazolo[1,5-a][1,4]benzodiazepine-2-carboxylic acid 
• 50330-90-0 8-chloro-6-(2-fluorophenyl)-4H-<1,2,4>triazolo<1,5-a><1,4>benzodiazepine-2-carboxamide 

Relevant articles and documents

PERIPHERALLY RESTRICTED GABA POSITIVE ALLOSTERIC MODULATORS FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME AND OTHER AILMENTS OF THE PERIPHERAL NERVOUS SYSTEM

The present invention provides compounds and compositions which are positive allosteric modulators of GABA-A receptors that selectively target the peripheral nervous system and organs of the body, and which do not pass through the blood-brain barrier. The compounds and compositions of the present invention are useful for treatment of diseases or disorders which are mediated by GABA-A neuronal activity, such as, for example, visceral pain, gut motility, irritable bowel syndrome, functional abdominal pain, functional idiopathic diarrhea, inflammatory bowel diseases, drug induced pain, bile salt malabsorption, lactase or other carbohydrate intolerance.

Structure and reactivity of a triazolo-benzodiazepine/oxalyl chloride adduct

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