41405-77-0 Usage
Description
3-Carboxyantipyrine is a metabolite of Antipyrine, a non-steroidal anti-inflammatory drug (NSAID) that is widely used as a probe for human oxidative drug metabolism. It is formed by various hepatic cytochrome P450 enzymes and plays a significant role in the assessment of drug metabolism and clearance.
Uses
Used in Pharmaceutical Industry:
3-Carboxyantipyrine is used as a metabolic marker for evaluating the activity of hepatic cytochrome P450 enzymes, which are crucial in the metabolism of numerous drugs and xenobiotics. This application is essential for understanding the metabolic profile of patients and tailoring drug dosages accordingly.
Used in Research and Development:
In the field of drug metabolism research, 3-carboxyantipyrine serves as a valuable tool for studying the metabolic pathways of NSAIDs and other drugs. It helps researchers identify and characterize the specific enzymes involved in the metabolism of these compounds, leading to a better understanding of drug interactions and potential side effects.
Used in Clinical Trials:
3-Carboxyantipyrine is utilized as a biomarker in clinical trials to assess the efficacy of new drugs and their impact on drug metabolism. By monitoring the levels of this metabolite, researchers can evaluate the effectiveness of new treatments and their potential to influence the metabolic processes in the body.
Used in Toxicology Studies:
In toxicology, 3-carboxyantipyrine is employed to investigate the potential toxic effects of drugs and other chemicals on the liver and other organs involved in drug metabolism. This information is vital for determining the safety of new drugs and understanding the mechanisms of drug-induced toxicity.
Used in Drug Metabolism Education:
3-Carboxyantipyrine serves as an educational tool for teaching students and professionals about the complexities of drug metabolism, the role of cytochrome P450 enzymes, and the importance of individualized drug therapy based on metabolic profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 41405-77-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,4,0 and 5 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 41405-77:
(7*4)+(6*1)+(5*4)+(4*0)+(3*5)+(2*7)+(1*7)=90
90 % 10 = 0
So 41405-77-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H10N2O3/c1-12-9(11(15)16)7-10(14)13(12)8-5-3-2-4-6-8/h2-7H,1H3,(H,15,16)
