4159-20-0 Usage
Description
3,4-didehydroretinoic acid, also known as a retinoic acid derivative, is a retinoid compound that is obtained by the 3,4-desaturation of the beta-ionone ring of all-trans-retinoic acid. It is a vital molecule with significant potential in various applications, particularly in the medical field.
Uses
Used in Pharmaceutical Industry:
3,4-didehydroretinoic acid is used as a therapeutic agent for the treatment of neuroinflammatory conditions. It plays a crucial role in modulating the immune response and reducing inflammation in the central nervous system, making it a promising candidate for the management of various neuroinflammatory disorders.
Used in Anticancer Applications:
Although not explicitly mentioned in the provided materials, 3,4-didehydroretinoic acid, being a retinoic acid derivative, may also have potential applications in cancer therapy. Retinoic acid and its derivatives have been known to exhibit anticancer properties by regulating cell differentiation, proliferation, and apoptosis. Further research may reveal its specific roles and mechanisms in cancer treatment.
Used in Drug Delivery Systems:
Similar to gallotannin, 3,4-didehydroretinoic acid may also benefit from novel drug delivery systems to enhance its bioavailability, delivery, and therapeutic outcomes. The development of organic and metallic nanoparticles or other advanced drug delivery platforms could improve the efficacy and safety of 3,4-didehydroretinoic acid in treating neuroinflammatory conditions and potentially other diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 4159-20-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,5 and 9 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 4159-20:
(6*4)+(5*1)+(4*5)+(3*9)+(2*2)+(1*0)=80
80 % 10 = 0
So 4159-20-0 is a valid CAS Registry Number.
InChI:InChI=1/C20H26O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6-12,14H,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
4159-20-0Relevant articles and documents
SYNTHETIC INVESTIGATIONS IN THE CHEMISTRY OF POLYENE COMPOUNDS LV. SYNTHESIS OF 9,13-DIMETHYL-7-(1,1,5-DIMETHYL-3,5-CYCLOHEXADIEN-6-YL)-7E,9E,11E,13E-NONATETRAEN-15-OIC ACID (VITAMIN A2 ACID) AND ITS ESTERS
Gorina, N. Yu.,Zakharova, N. I.,Filippova, T. M.,Samokhvalov, G. I.
, p. 1622 - 1628 (2007/10/02)
The condensation of 9-methyl-7-(1,1,5-trimethyl-5-cyclohexen-6-yl)-7,9,11-octatrien-13-one (the C18 ketone) with isobutyl monochloroacetate under the influence of potassium isobutoxide or tert-butoxide gave the glycidic ester of the C20 acid.Opening of th