41593-98-0

Basic information

• Product Name: N-benzyl-1,3-thiazol-2-amine
• CAS NO: 41593-98-0
• Molecular Formula: C₁₀H₁₀N₂S
• Molecular Weight: 190.2648
• Mol File: 41593-98-0.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 330.1°C at 760 mmHg
• Flash Point: 153.4°C
• Density: 1.249g/cm³
• Vapor Pressure: 0.00017mmHg at 25°C
• Refractive Index: 1.669
• CAS DataBase Reference: N-benzyl-1,3-thiazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-1,3-thiazol-2-amine(41593-98-0)
• EPA Substance Registry System: N-benzyl-1,3-thiazol-2-amine(41593-98-0)

Safety Data

• Hazardous Substances Data: 41593-98-0(Hazardous Substances Data)

Usage

General Description

N-benzyl-1,3-thiazol-2-amine is a chemical compound with the molecular formula C10H10N2S. It is a member of the thiazole class of compounds and is characterized by a thiazole ring structure containing a nitrogen and sulfur atom. The benzyl group attached to the thiazole ring gives the compound its aromatic nature. This chemical may have potential applications in medicinal chemistry and pharmaceutical research due to its structural and functional properties. It is important to handle this compound with care and use appropriate safety measures as it may be toxic if ingested or inhaled.

Upstream product

• 13053-82-2 N-(1,3-thiazol-2-yl)benzamide 
• 623-46-1 1,2-dichloro-2-ethoxyethane 
• 621-83-0 N-benzylthiourea 
• 97-97-2 chloroacetaldehyde dimethyl acetal 
• 75-07-0 acetaldehyde 
• 13243-76-0 benzylidene-1,3-thiazol-2-yl-amine 
• 17157-48-1 bromoacetaldehyde 
• 76384-86-6 iodo-1 thiocyanato-2 ethylene 
• 100-46-9 benzylamine 
• 96-50-4 2-thiazolylamine 
• 100-52-7 benzaldehyde 
• 100-39-0 benzyl bromide 
• 98-88-4 benzoyl chloride 
• 100-51-6 benzyl alcohol 

Downstream Products

• 101117-32-2 N-benzyl-N',N'-dimethyl-N-thiazol-2-yl-ethylenediamine 
• 50979-36-7 8-benzyl-5,7-dioxo-5,6,7,8-tetrahydro-thiazolo[3,2-a]pyrimidinylium betaine 
• 50979-41-4 8-benzyl-6-methyl-5,7-dioxo-5,6,7,8-tetrahydro-thiazolo[3,2-a]pyrimidinylium betaine 
• 39386-58-8 1-benzyl-2-oxo-4-thioxo-1,2,3,4-tetrahydro-thiazolo[3,2-a][1,3,5]triazinylium betaine 
• 41594-04-1 2-benzylimino-thiazole-3-carbothioic acid ethylcarbamoyl-amide 
• 39386-60-2 1-benzyl-2,4-dioxo-1,2,3,4-tetrahydro-thiazolo[3,2-a][1,3,5]triazinylium betaine 
• 63615-94-1 benzyl-(5-bromo-thiazol-2-yl)-amine 
• 13243-76-0 benzylidene-1,3-thiazol-2-yl-amine 
• 91265-84-8 anhydro-(6-ethyl-7-oxo-8-benzyl-5-hydroxythiazole[3,2-a]pyrimidinium hydroxide) 

Relevant articles and documents

Reductive Amination Revisited: Reduction of Aldimines with Trichlorosilane Catalyzed by Dimethylformamide─Functional Group Tolerance, Scope, and Limitations

Aldimines, generated in situ from aliphatic, aromatic, and heteroaromatic aldehydes and aliphatic, aromatic, and heteroaromatic primary or secondary amines, can be reduced with trichlorosilane in the presence of dimethylformamide (DMF) as an organocatalys

Sulfated polyborate: A dual catalyst for the reductive amination of aldehydes and ketones by NaBH4

An efficient, quick, and environment-friendly one-pot reductive amination of aldehydes or ketones was developed. In ethanol at 70 °C, a imination catalyzed by sulfated polyborate and further reduced by sodium borohydride yields various amines. The present method has many significant benefits, including a shorter reaction time, excellent yields, and a hassle-free, straightforward experimental process. The reaction has a wide range of applications due to its flexibility, including secondary amine for reductive amination.

Pd-PEPPSI-IPentAn Promoted Deactivated Amination of Aryl Chlorides with Amines under Aerobic Conditions

We report herein a highly efficient Pd-catalyzed amination by "bulky-yet-flexible" Pd-PEPPSI-IPentAn complexes. The relationship between the N-heterocyclic carbenes (NHCs) structure and catalytic properties was discussed. Sterically hindered (hetero)aryl chlorides and a variety of aliphatic and aromatic amines can be applied in this cross-coupling, which smoothly proceeded to provide desired products. The operationally simple protocol highlights the rapid access to CAr-N bond formation under mild conditions without the exclusion of air and moisture.