41604-19-7 Usage
Description
4-Bromo-2-fluorobiphenyl is a pale yellow crystalline compound that serves as an intermediate in the synthesis of various bio-active compounds, including non-steroidal anti-inflammatory drugs (NSAIDs). Its unique chemical structure, featuring a bromine atom at the 4th position and a fluorine atom at the 2nd position on the biphenyl backbone, endows it with specific properties that make it valuable in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
4-Bromo-2-fluorobiphenyl is used as a key intermediate for the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) due to its ability to be chemically modified to produce active pharmaceutical ingredients. These NSAIDs are widely used for their analgesic, antipyretic, and anti-inflammatory properties, helping to alleviate pain and reduce inflammation in various conditions.
Used in the Synthesis of Bio-active Compounds:
In addition to its role in the production of NSAIDs, 4-Bromo-2-fluorobiphenyl is also utilized as an intermediate in the preparation of other bio-active compounds. These compounds may have potential applications in various therapeutic areas, such as cardiovascular, neurological, and oncological treatments. The versatility of 4-Bromo-2-fluorobiphenyl in chemical reactions allows for the development of novel and effective pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 41604-19-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,6,0 and 4 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 41604-19:
(7*4)+(6*1)+(5*6)+(4*0)+(3*4)+(2*1)+(1*9)=87
87 % 10 = 7
So 41604-19-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H6ClF3O2S/c1-15(13,14)5-2-3-7(9)6(4-5)8(10,11)12/h2-4H,1H3
41604-19-7Relevant articles and documents
A mild and practical synthesis of biphenyl compounds
Liang, Shuang,Cao, Xiaohui,Yan, Xilong,Chen, Ligong
, p. 555 - 556 (2012)
A mild and practical synthetic route for biphenyls is established. Isopropyl nitrite was prepared from sodium nitrite, isopropanol and hydrochloric acid. The biphenyl compounds were obtained from the diazotisation of aniline derivatives with the generated isopropyl nitrite and the coupling reaction with benzene derivatives in the presence of CuCl as a catalyst in good yields.
AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME
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Paragraph 0193-0198; 0229-0233, (2021/04/20)
The present invention relates to an organic light emitting compound which is aromatic amine derivatives expressed as chemical formula A and has excellent light emitting properties such as brightness and light emitting efficiency compared with those of an existing light emitting material. Accordingly, an organic electroluminescent device comprising the same has excellent light emitting properties.
Aromatic amine derivatives having fluorenyl moiety and organic light-emitting diode including the same
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Paragraph 0215; 0222-0227; 0295-0299, (2020/03/24)
The present invention relates to aromatic amine derivatives with a fluorene structure and a light-emitting element including the same, and more specifically, to an organic light-emitting compound expressed as [Formula A] and a light-emitting element containing the same. [Formula A] In [Formula A], X1 or X8 and Ar1, Ar2 are specifically defined in the description of the invention.