41652-79-3

Basic information

• Product Name: 2-Allyl-6-Methylaniline
• Synonyms: 2-Allyl-6-Methylaniline
• CAS NO: 41652-79-3
• Molecular Formula: C₁₀H₁₃N
• Molecular Weight: 147.21692
• Mol File: 41652-79-3.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Allyl-6-Methylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Allyl-6-Methylaniline(41652-79-3)
• EPA Substance Registry System: 2-Allyl-6-Methylaniline(41652-79-3)

Safety Data

• Hazardous Substances Data: 41652-79-3(Hazardous Substances Data)

Usage

Classification

Aromatic amine

Common Uses

Manufacture of dyes, pigments, and industrial products

Physical Properties

Color: Pale yellow to brown
Odor: Slight amine odor

Toxicity

Considered to have low toxicity

Environmental Impact

Not expected to be harmful to the environment

Handling

Should be handled with care

Storage

Should be stored in a well-ventilated area

Upstream product

• 15316-91-3 N-allyl-o-toluidine 
• 7664-93-9 sulfuric acid 
• 95-53-4 o-toluidine 
• 1035570-51-4 2-(methoxymethyl)-6-methylaniline 
• 1826-67-1 vinyl magnesium bromide 
• 2622-05-1 allylmagnesium bromide 
• 74965-31-4 N-(tert-butoxycarbonyl)-o-toluidine 

Downstream Products

• 68461-08-5 2-Methyl-6-(1'-propenyl)anilin 
• 68460-57-1 N-(2-Allyl-6-methyl-phenyl)-2-chloro-N-methoxymethyl-acetamide 
• 68460-58-2 N-(2-Allyl-6-methyl-phenyl)-N-butoxymethyl-2-chloro-acetamide 
• 863968-47-2 6-methyl-2-[(Z)-1-propenyl]aniline 
• 863968-48-3 6-methyl-2-[(E)-1-propenyl]aniline 
• 66236-28-0 N-{6-methyl-2-[(Z)-1-propenyl]phenyl}methanesulfonamide 
• 863968-49-4 ethyl 2-methyl-6-[(Z)-1-propenyl]phenylcarbamate 
• 863968-50-7 ethyl 2-methyl-6-[(E)-1-propenyl]phenylcarbamate 
• 68460-83-3 2-Chloro-N-isopropoxymethyl-N-[2-methyl-6-((E)-propenyl)-phenyl]-acetamide 
• 68460-84-4 N-Butoxymethyl-2-chloro-N-[2-methyl-6-((E)-propenyl)-phenyl]-acetamide 
• 1309578-49-1 (E)-methyl 4-(3-methyl-2-(4-methylphenylsulfonamido)phenyl)but-2-enoate 
• 1309578-99-1 methyl 2-(7-methyl-1-tosylindolin-2-yl)acetate 
• 1257292-13-9 N-(2-allyl-6-methylphenyl)-4-methylbenzenesulfonamide 
• 1431884-74-0 C₁₅H₁₇NO₂ 

Relevant articles and documents

Synthesis of functionalized indoles via palladium-catalyzed cyclization of N-(2-allylphenyl) benzamide: A method for synthesis of indomethacin precursor

We developed an efficient method for synthesis of substituted N-benzoylindole via Pd(II)-catalyzed C-H functionalization of substituted N-(2-allylphenyl)benzamide. The reaction showed a broad substrate scope (including N-acetyl and N-Ts substrates) and substituted indoles were obtained in good to excellent yields. The most distinctive feature of this method lies in the high selectivity for N-benzoylindole over benzoxazine, and this is the first example of Pd(II)-catalyzed synthesis of substituted N-benzoylindole. Notably, this new method was applied for the synthesis of key intermediate of indomethacin.

One-pot Construction of Difluorinated Pyrrolizidine and Indolizidine Scaffolds via Copper-Catalyzed Radical Cascade Annulation

A convenient approach to the synthesis of diverse difluorinated nitrogen-containing polycycles via a copper-catalyzed radical cascade annulation of amine-containing olefins and ethyl bromodifluoroacetate was developed. Three new bonds, including a Csp3 ?CF2 and two C?N bonds, are forged simultaneously in this strategy. Through this strategy, a series of difluorinated pyrrolizidine and indolizidine derivatives have been conveniently synthesized in good yields. (Figure presented.).

Engaging electronic effects for atropselective [5+2]-photocycloaddition of maleimides

Atropisomeric maleimides were synthesized and subjected to atropselective [5+2]-photocycloaddition under direct irradiation to yield azepinone products with high enantio- (ee >98%) and diastereoselectivity (dr >98%). While the ee was dictated by the axial