4172-99-0 Usage
Description
1-Cyanocyclohexane acetonitrile is an organic compound that serves as a key intermediate in the synthesis of various pharmaceuticals and chemicals. It is characterized by its unique molecular structure, which consists of a cyclohexane ring with a nitrile group and a cyano group attached to it. 1-Cyanocyclohexane acetonitrile plays a crucial role in the production of certain medications, making it an essential component in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
1-Cyanocyclohexane acetonitrile is used as a key intermediate in the synthesis of Gabapentin, an anticonvulsant and analgesic medication. It is utilized for the production of this drug due to its ability to react with other compounds to form the desired active pharmaceutical ingredient (API). This makes 1-Cyanocyclohexane acetonitrile an essential component in the development and manufacturing process of Gabapentin.
Additionally, 1-Cyanocyclohexane acetonitrile may also be used as an intermediate in the synthesis of other pharmaceuticals and chemicals, depending on its reactivity and the specific requirements of the target compounds. Its versatility in chemical reactions makes it a valuable asset in the development of new medications and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 4172-99-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,7 and 2 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4172-99:
(6*4)+(5*1)+(4*7)+(3*2)+(2*9)+(1*9)=90
90 % 10 = 0
So 4172-99-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H12N2/c10-7-6-9(8-11)4-2-1-3-5-9/h1-6H2
4172-99-0Relevant articles and documents
Bis-morpholinophosphorylchloride, a novel reagent for the conversion of primary amides into nitriles
Rao, P. Purnachandra,Nowshuddin, Shaik,Jha, Anjali,Rao, B. Leela Maheswara,Divi, Murali K.,Rao
supporting information, (2021/01/21)
Bis-morpholinophosphorylchloride (Bmpc), in the presence of a base, is an efficient dehydrating agent for both aromatic and aliphatic primary amides, and gives corresponding nitriles under mild conditions in god yields and purity. During the reaction the enantiomeric integrity remains intact.
A PROCESS FOR THE PREPARATION OF GABAPENTIN
-
, (2014/01/09)
The present invention provides an improved process for the preparation of a compound of formula (I),
Carboxylate bioisosteres of gabapentin
Burgos-Lepley, Carmen E.,Thompson, Lisa R.,Kneen, Clare O.,Osborne, Simon A.,Bryans, Justin S.,Capiris, Thomas,Suman-Chauhan, Nirmala,Dooley, David J.,Donovan, Cindy M.,Field, Mark J.,Vartanian, Mark G.,Kinsora, Jack J.,Lotarski, Susan M.,El-Kattan, Ayman,Walters, Karen,Cherukury, Madhu,Taylor, Charles P.,Wustrow, David J.,Schwarz, Jacob B.
, p. 2333 - 2336 (2007/10/03)
A series of carboxylate bioisosteres of structures related to gabapentin 1 have been prepared. When the carboxylate was replaced by a tetrazole, this group was recognized by the α2-δ protein. Further characterization of α2-δ binding compounds 14a and 14b revealed a similar pattern of functional in vitro and in vivo activity to gabapentin 1.
