4180-62-5 Usage
General Description
Z-GLY-SER-OH is a chemical compound composed of three amino acids: glycine (Gly), serine (Ser), and an acetyl group (Z). The Z-GLY-SER-OH molecule functions as a peptide, with the amino acids linked together through peptide bonds. Z-GLY-SER-OH is primarily used in biochemical and pharmaceutical research as a building block for larger peptides or proteins. Additionally, Z-GLY-SER-OH may have potential applications in drug development, as the specific sequence of amino acids in the molecule can influence its biological activity and targeting properties. Overall, Z-GLY-SER-OH plays a crucial role in the study and development of biologically active compounds and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 4180-62-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,8 and 0 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4180-62:
(6*4)+(5*1)+(4*8)+(3*0)+(2*6)+(1*2)=75
75 % 10 = 5
So 4180-62-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H16N2O6/c16-7-10(12(18)19)15-11(17)6-14-13(20)21-8-9-4-2-1-3-5-9/h1-5,10,16H,6-8H2,(H,14,20)(H,15,17)(H,18,19)
4180-62-5Relevant articles and documents
Scandium(III) triflate-promoted serine/threonine-selective peptide bond cleavage
Ni, Jizhi,Sohma, Youhei,Kanai, Motomu
supporting information, p. 3311 - 3314 (2017/03/22)
The site-selective cleavage of peptide bonds is an important chemical modification that is useful not only for the structural determination of peptides, but also as an artificial modulator of peptide/protein function and properties. Here we report site-selective hydrolysis of peptide bonds at the Ser and Thr positions with a high conversion yield. This chemical cleavage relies on Sc(iii)-promoted N,O-acyl rearrangement and subsequent hydrolysis. The method is applicable to a broad scope of polypeptides with various functional groups, including a post-translationally modified peptide that is unsuitable for enzymatic hydrolysis. The system was further extended to site-selective cleavage of a native protein, Aβ1-42, which is closely related to the onset of Alzheimer's disease.