41803-67-2Relevant articles and documents
New Inhibitors of Breast Cancer Resistance Protein (ABCG2) Containing a 2,4-Disubstituted Pyridopyrimidine Scaffold
Krapf, Michael K.,Gallus, Jennifer,Vahdati, Sahel,Wiese, Michael
, p. 3389 - 3408 (2018/05/01)
Multidrug resistance (MDR) occurring during cancer chemotherapy is a major obstacle for effectiveness and response to therapy and is often caused by ATP-binding cassette (ABC) efflux transporters. Belonging to the family of ABC transporters, breast cancer