41844-71-7

Basic information

• Product Name: METHYL N-(METHOXYCARBONYL)-L-PHENYLALANINATE
• Synonyms: METHYL N-(METHOXYCARBONYL)-L-PHENYLALANINATE;Methyl (S)-2-Metho×ycarbonylaMino-3-phenyl-propionate;(S)-Methyl 2-((Methoxycarbonyl)aMino)-3-phenylpropanoate
• CAS NO: 41844-71-7
• Molecular Formula: C₁₂H₁₅NO₄
• Molecular Weight: 237.25
• Mol File: 41844-71-7.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: METHYL N-(METHOXYCARBONYL)-L-PHENYLALANINATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL N-(METHOXYCARBONYL)-L-PHENYLALANINATE(41844-71-7)
• EPA Substance Registry System: METHYL N-(METHOXYCARBONYL)-L-PHENYLALANINATE(41844-71-7)

Safety Data

• Hazardous Substances Data: 41844-71-7(Hazardous Substances Data)

Usage

General Description

METHYL N-(METHOXYCARBONYL)-L-PHENYLALANINATE is a chemical compound with the molecular formula C14H17NO4. It is an ester that consists of a methyl group, an N-methoxycarbonyl group, and an L-phenylalanine residue. METHYL N-(METHOXYCARBONYL)-L-PHENYLALANINATE is often used in the field of organic chemistry as a reagent in the synthesis of various pharmaceuticals and biologically active compounds. It has also been studied for its potential application in drug delivery systems and as a precursor for the synthesis of peptide-based materials. Additionally, it may have potential use in the development of new drug treatments due to its ability to modulate protein-protein interactions. Overall, METHYL N-(METHOXYCARBONYL)-L-PHENYLALANINATE is an important chemical compound with a range of potential applications in pharmaceutical and materials science research.

Upstream product

• 63-91-2 L-phenylalanine 
• 41844-56-8 2-Methoxycarbonyloxyimino-2-cyanoaethylacetat 
• 67-56-1 methanol 
• 142311-92-0 N-(L)-phenylalanine methyl ester 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 79-22-1 methyl chloroformate 
• 41844-91-1 N-methoxycarbonyl-L-phenylalanine 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 77357-58-5 2-((methoxycarbonyl)amino)-3-phenylpropanoic acid 
• 75-36-5 acetyl chloride 

Downstream Products

• 176972-61-5 (S)-(1-benzyl-3-chloro-2-oxopropyl)carbamic acid methyl ester 
• 263262-04-0 methyl N-methoxycarbonyl-N-methylphenylalaninate 
• 263261-71-8 N-(methoxycarbonyl)-N-methyl-L-phenylalanine 
• 127779-20-8 Saquinavir 
• 136522-17-3 cis-N-butyldecahydro-2-<2(R)-hydroxy-4-phenyl-3(S)-aminobutyl>-(4aS,8aS)-isoquinoline-3(S)-carboxamide 
• 137431-06-2 2-[3(S)-[(L-asparaginyl)-amino]-2(R)-hydroxy-4-phenylbutyl]-N-tert-butyl-decahydro(4aS,8aS)-isoquinoline-3(S)-carboxamide 
• 113089-22-8 (S)-2,2-Dichloro-3-hydroxy-4-methoxycarbonylamino-5-phenyl-pentanoic acid methyl ester 
• 113089-30-8 (4R,5S)-5-Benzyl-3,3-dichloro-4-hydroxy-pyrrolidin-2-one 
• 113089-29-5 (4S,5S)-5-Benzyl-3,3-dichloro-4-hydroxy-pyrrolidin-2-one 
• 84773-29-5 (S)-(+)-2-(N-methylamino)-3-phenylpropanol 

Relevant articles and documents

Urethanes synthesis from oxamic acids under electrochemical conditions

Urethane synthesis via oxidative decarboxylation of oxamic acids under mild electrochemical conditions is reported. This simple phosgene-free route to urethanes involves an in situ generation of isocyanates by anodic oxidation of oxamic acids in an alcoholic medium. The reaction is applicable to a wide range of oxamic acids, including chiral ones, and alcohols furnishing the desired urethanes in a one-pot process without the use of a chemical oxidant.

Catalysts and temperature driven melt polycondensation reaction for helical poly(ester-urethane)s based on natural L-amino acids

Catalyst and temperature driven melt polycondensation reaction was developed for natural L-amino acid monomers to produce new classes of poly(ester-urethane)s. Wide ranges of catalysts from alkali, alkali earth metal, transition metal and lanthanides were developed for the condensation of amino acid monomers with diols to yield poly(ester-urethane)s. A-B Diblock and A-B-A triblock species were obtained by carefully choosing mono- or diols in model reactions. More than two dozens of transition metal and lanthanide catalysts were identified for the polycondensation to yield high molecular weight poly(ester-urethane)s. Theoretical studies revealed that the carbonyl carbon in ester possessed low electron density compared to the carbonyl carbon in urethane which driven the thermo-selective polymerization process. Optical purity of the L-amino acid residues in the melt polycondensation process was investigated using D- and L-isomers and the resultant products were analyzed by chiral-HPLC and CD spectroscopy. CD analysis revealed that the amino acid based polymers were self-assembled as β-sheet and polyproline type II secondary structures. Electron and atomic force microscopic analysis confirmed the formation of helical nano-fibrous morphology in poly(ester-urethane)s. The newly developed melt polycondensation process is very efficient and optimized for wide range of catalysts to produce diverse polymer structures from natural L-amino acids.

Possible origin of electronic effects in Rh(I)-catalyzed enantioselective hydrogenation

(Chemical Equation Presented) Reducing the electron density of ligands switches the regioselectivity of Rh(I)-catalyzed hydrometalation. A reversal of the sense of chiral induction was also observed when chiral ligands are electronically tuned in the same